ArticleSurgical endoscopy2019
Long-term efficacy and safety of intralesional steroid injection plus oral steroid administration in preventing stricture after endoscopic submucosal dissection for esophageal epithelial neoplasms.
Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Efficacy and safety of triamcinolone acetonide in the prevention of esophageal stricture after endoscopic submucosal dissection: a meta-analysis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022Pooled it
- Risk factors of postoperative stricture after endoscopic submucosal dissection for superficial esophageal neoplasms: A meta-analysis.Medicine · 2021Pooled it
- Endoscopic radial incision combined with local injection of triamcinolone acetonide for refractory esophageal stenosis after endoscopy submucosal dissection.Updates in surgery · 2026Article
- A multicenter retrospective study on the risk factors of stricture formation after moderate circumferential defect resection in esophageal endoscopic submucosal dissection.Surgical endoscopy · 2026Observational
- Pharmacological therapy for preventing esophageal stricture after endoscopic submucosal dissection: a systematic review and network meta-analysis.International journal of surgery (London, England) · 2026Article
- Effectiveness of glucocorticoids in preventing esophageal stricture and predictors of stricture after esophageal ESD: 5 years of experience in a single medical center.Frontiers in medicine · 2025Article
- Predictors of stricture after endoscopic submucosal dissection of the esophagus and steroids application.World journal of gastrointestinal endoscopy · 2024Article
- Article
- Complications of endoscopic resection in the upper gastrointestinal tract.Clinical endoscopy · 2023Review
- Self-help inflatable balloon versus autologous skin-grafting surgery for preventing esophageal stricture after complete circular endoscopic submucosal dissection: a propensity score matching analysis.Surgical endoscopy · 2023Article
- Combined treatment of refractory benign stricture after esophageal endoscopic mucosal dissection: A case report.World journal of clinical cases · 2023Article
- Oral higher dose prednisolone to prevent stenosis after endoscopic submucosal dissection for early esophageal cancer.World journal of clinical cases · 2022Article
- Clinical effectiveness of short course oral prednisone for stricture prevention after semi-circumferential esophageal endoscopic submucosal dissection.Endoscopy international open · 2022Article
- The effects of oral steroid duration on stricture prevention after extensive endoscopic submucosal dissection for superficial esophageal cancer.Journal of thoracic disease · 2022Article
- Effects of steroid use for stenosis prevention after endoscopic submucosal dissection for cervical esophageal cancer.International journal of clinical oncology · 2022Article
- Advances in The Application of Regenerative Medicine in Prevention of Post-endoscopic Submucosal Dissection for Esophageal Stenosis.Journal of translational internal medicine · 2022Article
- Modified endoscopic radial incision and cutting method (M-RIC) for the treatment of refractory esophageal stricture.Surgical endoscopy · 2022Article
- Global research trend of esophageal squamous cell carcinoma from 2012 to 2022: a bibliometric analysis.Frontiers in oncology · 2022Article
- Simultaneous endoscopic submucosal dissection for synchronous multiple early esophageal squamous cell carcinoma: a propensity score-matched analysis.Surgical endoscopy · 2022Article
- Short- and long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell cancer in patients with prior gastrectomy.Surgical endoscopy · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic submucosal dissection (ESD) has been widely accepted as the treatment for early-stage esophageal epithelial neoplasms. However, stricture is a common complication after large-circumference ESD. This retrospective study is conducted to evaluate the efficacy and safety of intralesional steroid injection plus oral steroid administration in preventing esophageal stricture.
methods70 patients with a mucosal defect extending over more than two-thirds of the circumference after esophageal ESD for epithelial neoplasms were enrolled in this study. Those who received intralesional triamcinolone injection combined with oral prednisolone administration were assigned to the treatment group, while those who were treated without any prophylaxis of esophageal stricture were assigned to the control group. The primary observation result was the frequency of stricture. The secondary observation results were the number of endoscopic balloon dilation (EBD) sessions and rate of complications.
resultsCompared with the control group, the frequency of stricture (14.7% 5/34 patients vs. 51.5% 19/36 patients) and number of EBD sessions (mean 0.2 vs. 3.3) were significantly lower in the treatment group. One patient suffered from perforation in the treatment group and recovered with conservative treatment. None steroid-related complications were found during a long-term follow-up.
conclusionsIntralesional steroid injection plus oral steroid administration is safe and effective in preventing stricture following esophageal ESD for esophageal epithelial neoplasms with a mucosal defect extending no less than two-thirds of the circumference in a long-term follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.