ArticleEMBO molecular medicine2018
Targeting
Open access · goldAbstract read
In one paragraph
Article in EMBO molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 58 citations in OpenAlex.
- Intracellular Staphylococcus aureus triggers isolate-specific host transcriptional responses alongside TNF-R1 regulated cell fate decisions.Cell communication and signaling : CCS · 2026Article
- Comparative analysis of extracellular vesicles released from resting neutrophils under distinct pharmacological inhibition.Scientific reports · 2026Article
- The role of non-coding RNAs in Staphylococcus aureus infections: mechanisms, biomarkers, and therapeutic implications.Antonie van Leeuwenhoek · 2026Review
- Investigating the Therapeutic Efficacy of Quality-Controlled, miR-146a-5p-Enriched Small Extracellular Vesicles Derived From MSCs Against Idiopathic Pulmonary Fibrosis.Stem cell reviews and reports · 2026Article
- The AGO2-ATOX1 axis exacerbates inflammation in a mouse sepsis model.Central-European journal of immunology · 2026Article
- Host miRNA orchestration of mitophagy pathways during bacterial infection: current advances and future directions.Frontiers in microbiology · 2026Review
- Circulating microRNAs and Plasma Gelsolin as Biomarkers of Sepsis: Molecular Insights and Prospects for Precision Medicine.Biomolecules · 2025Review
- LncRNA NPTN-IT1-201 Ameliorates Depressive-like Behavior by Targeting miR-142-5p and Regulating Inflammation and Apoptosis via BDNF.Current medical science · 2024Article
- Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing.Journal of cell science · 2024Article
- A microRNA focus on acne.Dermatology reports · 2024Article
- Review
- Transcriptomic analysis of lipoteichoic acid‑treated undifferentiated and neutrophil‑like differentiated HL‑60 cells.Experimental and therapeutic medicine · 2024Article
- MicroRNAs in infectious diseases: potential diagnostic biomarkers and therapeutic targets.Clinical microbiology reviews · 2023Review
- Article
- Extracellular vesicles modulate key signalling pathways in refractory wound healing.Burns & trauma · 2023Review
- Macrophage Reprogramming with Anti-miR223-Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- MicroRNA serum profiles and chronic graft-versus-host disease.Blood advances · 2022Article
- Dysregulated miRNAs network in the critical COVID-19: An important clue for uncontrolled immunothrombosis/thromboinflammation.International immunopharmacology · 2022Review
- Beyond the Code: Noncoding RNAs in Skin Wound Healing.Cold Spring Harbor perspectives in biology · 2022Article
- Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation.Journal of neuroinflammation · 2022Article
Corrections and comments
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Authors and funding
25 authors at 9 institutions in 2 countries.
Maiko de KerckhoveDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Katsuya TanakaDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Takahiro UmeharaDepartment of Forensic Pathology and Science, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Momoko OkamotoDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Sotaro KanematsuLaboratory of Functional Genomics, Department of Medical Genome Science, Graduate of Frontier Science, The University of Tokyo, Tokyo, Japan.
Hiroko HayashiDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Hiroki YanoDepartment of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Soushi NishiuraDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Shiho TooyamaDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Yutaka MatsubayashiSchools of Biochemistry and Physiology, Pharmacology & Neuroscience, Faculty of Biomedical Sciences, University of Bristol, Bristol, UK.
Toshimitsu KomatsuDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Seongjoon ParkDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Yuka OkadaDepartment of Ophthalmology, Wakayama Medical University, Wakayama, Japan.
Rina TakahashiFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Yayoi KawanoFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Takehisa HanawaFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Keisuke IwasakiDepartment of Pathology, Sasebo City General Hospital, Sasebo Nagasaki, Japan.
Tadashige NozakiDepartment of Pharmacology, Faculty of Dentistry, Osaka Dental University, Hirakata Osaka, Japan.
Hidetaka TorigoeDepartment of Applied Chemistry, Faculty of Science, Tokyo University of Science, Tokyo, Japan.
Kazuya IkematsuDepartment of Forensic Pathology and Science, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Yutaka SuzukiLaboratory of Functional Genomics, Department of Medical Genome Science, Graduate of Frontier Science, The University of Tokyo, Tokyo, Japan.
Katsumi TanakaDepartment of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Paul MartinSchools of Biochemistry and Physiology, Pharmacology & Neuroscience, Faculty of Biomedical Sciences, University of Bristol, Bristol, UK.ORCID 0000-0002-2665-5086
Isao ShimokawaDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan.
Ryoichi MoriDepartment of Pathology, Nagasaki University School of Medicine and Graduate School of Biomedical Sciences, Nagasaki, Japan ryoichi@nagasaki-u.ac.jp.ORCID 0000-0002-7596-9620
Nagasaki University · JPTokyo University of Science · JPEhime Prefectural Central Hospital · JPThe University of Tokyo · JPKing's College London · GBOsaka Dental University · JPSasebo City General Hospital · JPUniversity of Bristol · GBWakayama Medical University · JP
Funding
Wellcome TrustWellcome Trust 097791/Z/11/Z
Abstract
Argonaute 2 bound mature microRNA (Ago2-miRNA) complexes are key regulators of the wound inflammatory response and function in the translational processing of target mRNAs. In this study, we identified four wound inflammation-related Ago2-miRNAs (
Indexed as
AnimalsCells, CulturedHumansInflammationMiceMice, KnockoutMicroRNAsNeutrophilsStaphylococcal InfectionsStaphylococcus aureusWound InfectionMicroRNAsMIR223, humanMIRN223 microRNA, mouseinflammationmiR‐223neutrophilskin wound healingStaphylococcus aureus
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.