Evidence map›Paper›PMID 30171031›Full record

ReviewHaematologica2018

European Myeloma Network recommendations on tools for the diagnosis and monitoring of multiple myeloma: what to use and when.

Jo Caers, Laurent Garderet, K Martin Kortüm, Michael E O'Dwyer, Niels W C J van de Donk, Mascha Binder, Sandra Maria Dold, Francesca Gay, Jill Corre, Yves Beguin and 15 more

Open access · goldAbstract readReview
In one paragraph

Review in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 148 citations in OpenAlex.

  1. EANM guidelines on the use of [European journal of nuclear medicine and molecular imaging · 2024
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 17 institutions in 10 countries.

Jo CaersDepartment of Hematology, University Hospital of Liege, Belgium jo.caers@chu.ulg.ac.be.
Laurent GarderetDepartment of Hematology, Hopital Saint Antoine, Paris, France.
K Martin KortümDepartment of Internal Medicine II, University Hospital of Wuerzburg, Germany.
Michael E O'DwyerDepartment of Hematology, National University of Ireland Galway, Ireland.
Niels W C J van de DonkDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Mascha BinderDepartment of Internal Medicine II, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sandra Maria DoldDepartment of Medicine I, Hematology, Oncology & Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Francesca GayDepartment of Hematology-Oncology, University Hospital Città della Salute e della Scienza, Torino, Italy.
Jill CorreUnit for Genomics in Myeloma, Institut Universitaire du Cancer - Oncopole, Toulouse, France.
Yves BeguinDepartment of Hematology, University Hospital of Liege, Belgium.
Heinz LudwigWilhelminen Cancer Research Institute, Vienna, Austria.
Alessandra LaroccaDepartment of Hematology-Oncology, University Hospital Città della Salute e della Scienza, Torino, Italy.
Christoph DriessenDepartment of Oncology and Hematology, Cantonal Hospital St. Gallen, Switzerland.
Meletios A DimopoulosSchool of Medicine, National and Kapodistrian University of Athens, Greece.
Mario BoccadoroDepartment of Hematology-Oncology, University Hospital Città della Salute e della Scienza, Torino, Italy.
Martin GramatzkiDivision of Stem Cell Transplantation and Immunotherapy, University of Kiel, Germany.
Sonja ZweegmanDepartment of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Hermann EinseleDepartment of Internal Medicine II, University Hospital of Wuerzburg, Germany.
Michele CavoSeragnoli 'Institute of Hematology, Bologna University School of Medicine, Italy.
Hartmut GoldschmidtDepartment of Hematology, Rheumatology and Oncology, University Hospital Heidelberg, Germany.
Pieter SonneveldDepartment of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Michel DelforgeDepartment of Hematology, University Hospital Leuven, Belgium.
Holger W AunerCentre for Haematology, Hammersmith Hospital, Imperial College London, UK.
Evangelos TerposSchool of Medicine, National and Kapodistrian University of Athens, Greece.
Monika EngelhardtDepartment of Medicine I, Hematology, Oncology & Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAmsterdam UMC Location Vrije Universiteit Amsterdam · NLNational and Kapodistrian University of Athens · GRUniversitätsklinikum Würzburg · DEUniversity of Freiburg · DEUniversity of Liège · BEChristian-Albrechts-Universität zu Kiel · DEErasmus MC Cancer Institute · NLHammersmith Hospital · GBHeidelberg University · DEInstitut universitaire du cancer de Toulouse Oncopole · FRKantonsspital St. Gallen · CHKU Leuven · BEOllscoil na Gaillimhe – University of Galway · IESorbonne Université · FRUniversität Hamburg · DEWilhelminen Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of multiple myeloma can be challenging, even for experienced physicians, and requires close collaboration between numerous disciplines (orthopedics, radiology, nuclear medicine, radiation therapy, hematology and oncology) before the final diagnosis of myeloma is made. The definition of multiple myeloma is based on the presence of clinical, biochemical, histopathological, and radiological markers of disease. Specific tests are needed both at presentation and during follow-up in order to reach the correct diagnosis and characterize the disease precisely. These tests can also serve prognostic purposes and are useful for follow-up of myeloma patients. Molecular analyses remain pivotal for defining high-risk myeloma and are used in updated patient stratifications, while minimal residual disease assessment via flow cytometry, molecular techniques and radiological approaches provides additional prognostic information on patients' long-term outcome. This pivotal information will guide our future treatment decisions in forthcoming clinical trials. The European Myeloma Network group updated their guidelines on different diagnostic recommendations, which should be of value to enable appropriate use of the recommendations both at diagnosis and during follow-up.

Indexed as

Multiple MyelomaPractice Guidelines as Topic

Identifiers

PMID30171031
PMCPMC6278986
OpenAlexW2889243328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.