Observational studyBMC ophthalmology2018
Effect of amblyopia treatment on choroidal thickness in hypermetropic anisometropic amblyopia using swept-source optical coherence tomography.
Observational study in BMC ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Binocular Vision Anomalies: An Update on Prevalence, Impact, Technological and Treatment Developments and Current Challenges.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Review
- Article
- Article
- Short-term effects of occlusion therapy and optical correction on microvasculature in monocular amblyopia: a retrospective case-control study.Scientific reports · 2023Article
- Evaluation of Choroidal Vascular Structure in Hyperopic Anisometropic Amblyopia.Beyoglu eye journal · 2023Article
- How does anisometropia affect the choroidal vascularity index?Indian journal of ophthalmology · 2022Article
- Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography.Frontiers in medicine · 2022Article
- Choroidal and Macular Thickness in Eyes with Amblyopia.Beyoglu eye journal · 2021Article
- Choroidal vessel density in unilateral hyperopic amblyopia using en-face optical coherence tomography.BMC ophthalmology · 2020Article
- Effect of optical correction on choroidal structure in children with anisohypermetropic amblyopia.PloS one · 2020Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRecent studies using optical coherence tomography (OCT) have indicated that choroidal thickness (CT) in the anisometropic amblyopic eye is thicker than that of the fellow and normal control eyes. However, it has not yet been established as to how amblyopia affects the choroid thickening. The purpose of the present study was to investigate the effect of amblyopia treatment on macular CT in eyes with anisometropic amblyopia using swept-source OCT.
methodsThirteen patients (mean age: 6.2 ± 2.4 years) with hypermetropic anisometropic amblyopia were included in this study. Visual acuity (VA), axial length (AL), and CT were measured at the enrollment visit and at the final visit, after at least 6 months of treatment. CT measurements were corrected for magnification error and were automatically analyzed using built-in software and divided into three macular regions (subfoveal choroidal thickness (SFCT), center 1 mm, and center 6 mm). A one-way analysis of covariance using AL as a covariate was performed to determine whether CT in amblyopic eyes changed after amblyopia treatment.
resultsThe average observation period was 22.2 ± 11.0 months. After treatment, VA (logMAR) improvement in the amblyopic eyes was 0.41 ± 0.19 (p < 0.001). SFCT, center 1 mm CT, and center 6 mm CT were significantly thicker in the amblyopic eyes compared with the fellow eyes both before and after treatment (p < 0.05 for all comparisons). There were no significant changes in SFCT, center 1 mm CT, or center 6 mm CT before and after treatment in the amblyopic (p = 0.25, 0.21, and 0.84, respectively) and fellow (p = 0.75, 0.84, and 0.91, respectively) eyes. The correlation between changes in logMAR versus changes in CT after treatment was not significant.
conclusionsAlthough VA in amblyopic eyes was significantly improved after treatment, the choroid thickening of anisometropic amblyopic eyes persisted, and there was no significant change found in the CT after the treatment. Our findings suggest that thickening of the CT in amblyopia is not directly related to visual dysfunction.
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