Evidence map›Paper›PMID 30170533›Full record

ArticleInternational journal of STD & AIDS2019

Oral and vaginal HIV pre-exposure prophylaxis product attribute preferences among female sex workers in the Mexico-US border region.

H A Pines, S A Strathdee, C W Hendrix, C C Bristow, A Harvey-Vera, C Magis-Rodríguez, G Martinez, S J Semple, T L Patterson

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. "Protected Means Armed": Perspectives on Pre-Exposure Prophylaxis (PrEP) Among Women Who Engage in Sex Work and Use Drugs in Kazakhstan.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

H A Pines1 Department of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-7173-1981
S A Strathdee1 Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
C W Hendrix2 Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
C C Bristow1 Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
A Harvey-Vera1 Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
C Magis-Rodríguez3 Centro Nacional para la Prevención y Control del VIH/SIDA (CENSIDA; National Center for HIV/AIDS Prevention and Control), Ministry of Health, Mexico City, Mexico.
G Martinez4 Federacion Mexicana de Asociaciones Privadas, Ciudad Juarez, Chihuahua, Mexico.
S J Semple5 Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
T L Patterson5 Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Tissue pharmacology imaging and modelingU19AI113127 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MCGOWAN, IAN MICHAEL · 2014 to 2018
$20.7M
Impact of Drug Policy Reform on the HIV Risk Environment among IDUs in TijuanaR37DA019829 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2010 to 2019
$6.7M
Texting intervention to sustain HIV prevention in women in high-drug-use contextsR01DA039071 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATTERSON, THOMAS L. · 2015 to 2019
$3.3M
Sexual Networks and HIV Transmission Clusters among Substance Using MSMK01DA040543 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PINES, HEATHER ALISA · 2015 to 2019
$901k
NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI094189NIAID NIH HHS U19 AI113127NIDA NIH HHS K01 DA040543NIDA NIH HHS R01 DA039071NIDA NIH HHS R37 DA019829
6 · The paper itself

Abstract

To assess the potential uptake of HIV pre-exposure prophylaxis (PrEP) products among female sex workers (FSWs) vulnerable to HIV infection, we examined the influence of product attributes on willingness to use products among 271 HIV-negative FSWs in Tijuana and Ciudad Juarez, Mexico (2016-2017). Via five-point Likert scale ratings, participants indicated their willingness to use hypothetical products with six attributes: formulation (pill, gel, liquid, or ring), frequency of use (daily, on-demand, or monthly), cost per use (10 or 200 pesos), effectiveness (40% or 80%), side effects (none or mild), and access point (healthcare clinic or non-governmental organization). Conjoint analysis was used to determine the impact of attributes on product ratings and identify preferred product attributes. Multinomial logistic regression was used to identify factors associated with formulation preferences. In both cities, formulation and frequency of use had the greatest impact on ratings. Participants in Ciudad Juarez indicated a strong preference for oral pills, whereas participants in Tijuana indicated roughly equal preferences for oral pills and vaginal gels. Monthly product use was preferred in both cities. Compared to preferring oral pills (38%), preferring vaginal gels (28%) was associated with practicing vaginal lubrication (adjusted odds ratio = 2.08; 95% confidence interval: 1.07-4.04). Oral PrEP may be acceptable to many FSWs in Tijuana and Ciudad Juarez; however, continued development of behaviorally-congruent vaginal PrEP products may also facilitate uptake and ensure sufficient coverage.

Indexed as

Patient PreferenceAdministration, IntravaginalAdministration, OralAdultFemaleHIV InfectionsHumansMexicoMiddle AgedPatient Acceptance of Health CarePre-Exposure ProphylaxisSex WorkSex WorkersTabletsUnited StatesVaginal Creams, Foams, and JelliesTabletsVaginal Creams, Foams, and Jelliesfemale sex workersHIVMexicoPre-exposure prophylaxispreferences

Identifiers

PMID30170533
PMCPMC6391168

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.