SynthesisMedicine2018
Short-term and long-term outcomes of liver transplantation using moderately and severely steatotic donor livers: A systematic review.
Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Practice Guidelines for Liver Transplantation in Saudi Arabia.Saudi medical journal · 2021Guideline
- Donor steatosis in the metabolic dysfunction-associated steatotic liver disease era: a retrospective analysis of challenges and outcomes in living donor liver transplantation.Clinical transplantation and research · 2026Article
- Steatotic liver disease and liver transplantation: Candidate selection and post-transplant management.JHEP reports : innovation in hepatology · 2026Review
- Changing liver utilization and discard rates in clinical transplantation in the ex-vivo machine preservation era.Frontiers in medical technology · 2023Review
- Liver transplantation in the era of non-alcoholic fatty liver disease/metabolic (dysfunction) associated fatty liver disease: the dilemma of the steatotic liver graft on transplantation and recipient survival.Hepatobiliary surgery and nutrition · 2022Article
- [Nonalcoholic fatty liver disease and liver transplantation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Review
- Hepatic macrosteatosis in the US pediatric deceased liver donor population.Pediatric transplantation · 2022Article
- An Update on Usage of High-Risk Donors in Liver Transplantation.Journal of clinical medicine · 2021Review
- Selected liver grafts from donation after circulatory death can be safely used for retransplantation - a multicenter retrospective study.Transplant international : official journal of the European Society for Organ Transplantation · 2020Article
- Acute Kidney Injury Patterns Following Transplantation of Steatotic Liver Allografts.Journal of clinical medicine · 2020Article
- A pilot study of ex-vivo MRI-PDFF of donor livers for assessment of steatosis and predicting early graft dysfunction.PloS one · 2020Article
- Higher thresholds for the utilization of steatotic allografts in liver transplantation: Analysis from a U.S. national database.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to perform a systemic review of the studies addressing the use of moderately and severely steatotic donor livers for liver transplantation.
methodsWe searched the following electronic databases from January 1, 1989, to August 1, 2017: PubMed, EMBASE, Science Citation Index Expanded, and the Cochrane Library. In addition, reference lists were scanned to identify any additional reports. The quality of published papers was assessed. The main outcomes of the use of moderately and severely steatotic donor livers for liver transplantation, including primary nonfunction, short-term mortality, and long-term mortality, were extracted for pooled analysis.
resultsLiterature searches identified 16 studies that met the inclusion criteria. There were no randomized controlled studies, and all of the studies were retrospective or prospective case series. From a total of 3226 subjects (532 moderately and severely steatotic donor livers and 2694 controls), we found a significant increase in primary nonfunction [odds ratio (OR): 2.47, 95% confidence interval (95% CI): 1.44-4.27], and a trend of increase in 1-month patient mortality (OR: 1.90, 95% CI: 0.98-3.71) with the use of moderately and severely steatotic donor livers, whereas the 1-year mortality was relatively less influenced.
conclusionThe use of moderately and severely steatotic livers is associated with unfavorable short-term outcomes, but long-term outcomes are relatively less influenced.
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Registered trials
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