SynthesisMedicine2018
Laparoscopic versus open nephroureterectomy for upper urinary tract urothelial carcinoma: A systematic review and meta-analysis.
Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Oncological outcomes of laparoscopic versus open nephroureterectomy for the treatment of upper tract urothelial carcinoma: an updated meta-analysis.World journal of surgical oncology · 2021Pooled it
- Open Nephroureterectomy Compared to Laparoscopic in Upper Urinary Tract Urothelial Carcinoma: A Meta-Analysis.Frontiers in surgery · 2021Pooled it
- Upper tract urothelial carcinoma arising in a horseshoe kidney with ureteropelvic junction obstruction: a case report.Urology case reports · 2026Article
- A novel one-position versus conventional surgical approach for the treatment of upper urinary tract urothelial carcinoma: a multicenter cohort study based in western China.International urology and nephrology · 2026Article
- Arteriovenous Malformation of the Ureter: A Rare Urological Entity Managed With Endoscopic Laser Ablation.Case reports in urology · 2026Article
- Comparison of Oncological Outcomes between Transperitoneal and Retroperitoneal Approaches in Laparoscopic Nephroureterectomies for Upper Tract Urothelial Carcinoma.Medicina (Kaunas, Lithuania) · 2024Article
- Comparison of survival outcomes between laparoscopic versus open radical nephroureterectomy in upper tract urothelial cancer patients: Experiences of a tertiary care single center.Current urology · 2023Article
- Comparison of oncological outcomes for hand-assisted and pure laparoscopic radical nephroureterectomy: results from the Taiwan Upper Tract Urothelial Cancer Collaboration Group.Surgical endoscopy · 2022Article
- Single-session laparoscopic cystectomy and nephroureterectomy: is it real and useful choice of treatment or fiction?Journal of surgical case reports · 2021Article
- Complete transperitoneal laparoscopic nephroureterectomy in a single position for upper urinary tract urothelial carcinoma and comparative outcomes.World journal of surgical oncology · 2021Article
- Diagnostic challenges and treatment strategies in the management of upper-tract urothelial carcinoma.Turkish journal of urology · 2021Review
- Article
- The nephroureterectomy: a review of technique and current controversies.Translational andrology and urology · 2020Review
- Laparoscopic radical cystectomy and nephroureterectomyMedicine and pharmacy reports · 2020Article
- Perioperative complications and adverse sequelae of radical nephroureterectomy.Translational andrology and urology · 2020Review
- Evaluation of Patterns of Presentation, Practice, and Outcomes of Upper Tract Urothelial Cancer: Protocol for an Observational, International, Multicenter, Cohort Study by the Clinical Research Office of the Endourology Society.JMIR research protocols · 2020Article
- A New Surgical Technique of Combination Retroperitoneal with Transperitoneal Laparoscopic Nephroureterectomy in a Single Position and Comparative Outcomes.Cancer management and research · 2020Article
- Surgical and oncological outcome after laparoscopic versus open nephroureterectomy for non-metastatic, upper-tract urothelial carcinoma. A single-centre experience.Saudi medical journal · 2020Article
- Optimal Management of Upper Tract Urothelial Carcinoma: an Unmet Need.Current treatment options in oncology · 2019Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the efficacy and safety of laparoscopic nephroureterectomy (LNU) and open nephroureterectomy (ONU) for the treatment of upper urinary tract urothelial carcinoma (UTUC).
methodsPubMed, Embase, and Cochrane databases were selected for systematic review of trials that compared outcomes of LNU and ONU. Meta-analysis was performed using RevMan 5.3 and STATA 13.0 software.
resultsLNU was associated with longer operation time (P < .001), shorter hospital stay (P < .001), less blood loss (P = .006) and lower rate of transfusion (P < .001). The occurrence of complications, including minor (P = .52), major (P = .21) and total complications (P = .19) were similar between LNU and ONU. There was no significant difference in the rate of 5-year recurrence-free survival (P = .90), 5-year cancer-specific survival (P = .12), and 5-year overall survival (P = .11) as well as 2-year RFS (P = .84), 2-year CSS (P = .86), and 2-year OS (P = .25).
conclusionOur results indicated that LNU is a safe and effective method to treat UTUC. Given the limitations of this study, further multicenter, randomized trials are required to confirm these findings.
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Registered trials
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