Evidence map›Paper›PMID 30170222›Full record

ArticleAtherosclerosis2018

Diastolic blood pressure predicts coronary plaque volume in patients with coronary artery disease.

Mohamad Saleh, Abdulhamied Alfaddagh, Tarec K Elajami, Hasan Ashfaque, Huzifa Haj-Ibrahim, Francine K Welty

Open access · greenAbstract read
In one paragraph

Article in Atherosclerosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mohamad SalehDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Abdulhamied AlfaddaghDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Tarec K ElajamiDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Hasan AshfaqueDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Huzifa Haj-IbrahimDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Francine K WeltyDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA. Electronic address: fwelty@bidmc.harvard.edu.
Beth Israel Deaconess Medical Center · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Weight Loss, Inflammation, and Vascular RemodelingP50HL083813 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WELTY, FRANCINE K · 2006 to 2015
$13.0M
NCATS NIH HHS UL1 TR001102NHLBI NIH HHS P50 HL083813
6 · The paper itself

Abstract

BACKGROUND AND

aimsHypertension is associated with increased clinical and subclinical coronary artery disease (CAD); however, the relationship between blood pressure and coronary plaque volume is unclear. We examined the effect of systolic blood pressure (SBP) and diastolic blood pressure (DBP) on coronary artery plaque volume.

methods285 subjects with stable CAD on statin therapy underwent coronary computed tomographic angiography to measure volume of fatty, fibrous, noncalcified, calcified and total coronary plaque.

resultsMean (SD) age was 63.1 (7.7); mean (SD) LDL-C, 78.7 mg/dL (28.5). Compared to the highest DBP tertile (>76 mmHg), those in the lowest DBP tertile (≤68 mmHg) had lower volumes of fatty: 10.0 vs. 7.7 mm

conclusionsLevel of DBP predicts coronary plaque with a DBP tertile ≤68 mmHg associated with the least amount of coronary plaque in subjects with LDL-C < 80 mg/dL.

Indexed as

Blood PressureComputed Tomography AngiographyPlaque, AtheroscleroticAdultAgedAged, 80 and overCoronary AngiographyCoronary Artery DiseaseCoronary VesselsCross-Sectional StudiesDiastoleFemaleFibrosisHumansHypertensionMaleCoronary computed tomographic angiographyCoronary plaqueDiastolic blood pressureSystolic blood pressure

Identifiers

PMID30170222
PMCPMC7963403
OpenAlexW2884445145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.