Evidence map›Paper›PMID 30169811›Full record

Trial reportThe journals of gerontology. Series B, Psychological sciences and social sciences2019

Can Intraindividual Variability in Cognitive Speed Be Reduced by Physical Exercise? Results From the LIFE Study.

Allison A M Bielak, Christopher R Brydges

Abstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series B, Psychological sciences and social sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. A Comparison of the Effect of Physical Activity and Cognitive Training on Dual-Task Performance in Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Trial
  2. Using Cognitive Intraindividual Variability to Measure Intervention Effectiveness: Results from the Baltimore Experience Corps Trial.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Trial
  3. Review
  4. Research progress on multicomponent physical exercise for patients with neurocognitive impairment.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Review
  5. Article
  6. Gait Performance as an Indicator of Cognitive Deficit in Older People.International journal of environmental research and public health · 2021
    Article
  7. Article
  8. The Impact of a Sustained Cognitive Engagement Intervention on Cognitive Variability: The Synapse Project.Journal of cognitive enhancement : towards the integration of theory and practice · 2019
    Article
  9. Leveraging the Power of Networks to Support Healthy Aging.The journals of gerontology. Series B, Psychological sciences and social sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Allison A M BielakDepartment of Human Development and Family Studies, Colorado State University, Fort Collins.
Christopher R BrydgesDepartment of Human Development and Family Studies, Colorado State University, Fort Collins.

Funding

UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
Using Cognitive Intraindividual Variability to Measure Lifestyle Interventions Admin SupplementR03AG055748 · NIA · COLORADO STATE UNIVERSITY · PI BIELAK, ALLISON · 2017 to 2018
$304k
NIA NIH HHS R03 AG055748NIA NIH HHS U01 AG022376
6 · The paper itself

Abstract

objectivesFindings are mixed regarding the potential to improve older adults' cognitive ability via training and activity interventions. One novel sensitive outcome may be intraindividual variability (IIV) in cognitive speed, or moment-to-moment changes in a person's performance. The present article evaluated if participants who participated in a moderate physical activity intervention showed a reduction in IIV, compared with a successful aging education control group.

methodFor approximately 2.6 years, sedentary adults aged 70-90 years participated in the Lifestyle Interventions and Independence for Elders (LIFE) Study (n = 1,635), a multisite Phase 3 randomized controlled trial to reduce major mobility disability. They completed 4 reaction time tests at baseline and at approximately 24 months post-test.

resultsAnalyses were conducted following both the intent-to-treat principle and complier average casual effect modeling. Results indicated that participants in the physical activity group did not show a reduction in their IIV. DISCUSSION: The lack of a significant reduction in IIV may be due to the mild nature of the physical activity program and the cognitively healthy sample. It is also possible that other types of lifestyle activity interventions (e.g., social and cognitive engagement) can elicit reductions in IIV for older adults.

Indexed as

CognitionAgedAged, 80 and overExerciseFemaleHumansMaleNeuropsychological TestsCognitionExerciseInterventionsPlasticityServices

Identifiers

PMID30169811
PMCPMC6777765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.