Evidence map›Paper›PMID 30169796›Full record

ArticleInternational journal of epidemiology2018

Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women's Health Study and the Shanghai Men's Health Study.

Xiaona Liu, Wanghong Xu, Hui Cai, Yu-Tang Gao, Honglan Li, Bu-Tian Ji, Xiang Shu, Thomas Wang, Robert E Gerszten, Wei Zheng and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in International journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Metabolic diseases in the East Asian populations.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Relevance of Indian traditional tisanes in the management of type 2 diabetes mellitus: A review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Green tea and metabolic syndrome: A 10-year research update review.Iranian journal of basic medical sciences · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Xiaona LiuDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Wanghong XuDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Hui CaiDivision of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Yu-Tang GaoDepartment of Epidemiology, Shanghai Jiaotong University Renji Hospital, Shanghai, China.
Honglan LiDepartment of Epidemiology, Shanghai Jiaotong University Renji Hospital, Shanghai, China.
Bu-Tian JiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Xiang ShuDivision of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Thomas WangDivision of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Robert E GersztenDivision of Cardiovascular Medicine, Beth Israel Deaconess Hospital, Boston, MA, USA.
Wei ZhengDivision of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Yong-Bing XiangDepartment of Epidemiology, Shanghai Jiaotong University Renji Hospital, Shanghai, China.
Xiao-Ou ShuDivision of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Vanderbilt University · USFudan University · CNRenji Hospital · CNNational Cancer Institute · US

Funding

Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
Shanghai Men's Health StudyUM1CA173640 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU · 2013 to 2017
$4.9M
Metabolite profiles and the risk of diabetes in AsiansR01DK108159 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GERSZTEN, ROBERT E, SHU, XIAO-OU · 2016 to 2019
$2.6M
NCI NIH HHS UM1 CA173640NCI NIH HHS UM1 CA182910NIDDK NIH HHS R01 DK108159
6 · The paper itself

Abstract

Background: Epidemiological evidence on the association between tea consumption and the risk of type 2 diabetes (T2D) is inconsistent. This study prospectively investigated whether green tea drinking affects the risk of T2D. Methods: This study included participants from the Shanghai Women's Health Study (N = 67 058) and the Shanghai Men's Health Study (N  =  52 315) without diabetes at study enrolment. Details of tea consumption, including types and amounts, were collected at the baseline and follow-up survey. Incident T2D was identified through follow-up surveys. Plasma level of caffeine metabolite was measured in a nested case-control study involving 592 diabetes case-control pairs. Cox regression analysis, with tea drinking as a time-dependent variable and covariates adjusted for by a propensity score, was applied to estimate the hazard ratio (HR) and 95% confidence interval (CI) for T2D risk. Logistic regression analysis was applied to evaluate the association between caffeine metabolites and T2D risk. Results: Current green tea drinkers had an increased risk of T2D compared with non-current drinkers [HR = 1.20 (95% CI = 1.14-1.27)], and a dose-response relationship was observed for duration of drinking tea and the amount of tea consumed [P for trend <0.001]. The increased risk associated with green tea drinking was observed in both women and men, across the entire period of follow-up, with HR (95% CI) of 1.08 (0.97-1.19) within 5 years of follow-up, 1.22 (1.12-1.32) during the period of 5-10 years of follow-up and 1.16 (1.03-1.30) after 10 years of follow-up. This association did not vary significantly by body mass index, waist-to-hip circumference ratio or smoking status. Plasma level of caffeine was also associated with increased diabetes risk (P  =  0.03), confirming the results based on self-reported tea drinking. Conclusions: Green tea drinking was associated with an increased risk of T2D in Chinese adults. The mechanisms underlying the association need to be elucidated.

Indexed as

AdultAgedCaffeineCase-Control StudiesChinaDiabetes Mellitus, Type 2FemaleHumansLogistic ModelsMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsTeaCaffeineTea

Identifiers

PMID30169796
PMCPMC6280927
OpenAlexW2889210169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.