Evidence map›Paper›PMID 30168406›Full record

ArticlePrimary health care research & development2018

Urine cultures and antibiotics for urinary tract infections in Dutch general practice.

Karlijn M J Ganzeboom, Annemarie A Uijen, Doreth T A M Teunissen, Willem J J Assendelft, Hans J G Peters, Jeannine L A Hautvast, Cornelia H M Van Jaarsveld

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Primary health care research & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Nitrofurantoin failure in males with an uncomplicated urinary tract infection: a primary care observational cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Observational
  6. Article
  7. Article
  8. Observational
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Karlijn M J GanzeboomMedical Student, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Annemarie A UijenCoordinator Famely Medicine Network, General Practitioner, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Doreth T A M TeunissenGeneral Practitioner, Senior Researcher, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Willem J J AssendelftProfessor in Primary Care, Head of Department, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Hans J G PetersDatamanager, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Jeannine L A HautvastSenior Researcher in Infectious Diseases, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Cornelia H M Van JaarsveldSenior Epidemiologist, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-4269-0041
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary tract infections (UTIs) are common in general practice, and antibiotic resistance is often seen. Urine cultures are advised by the Dutch national UTI guideline for patients at high risk of UTI complications. Prudent use of antibiotics and taking into account national guidelines and urine culture results are important to combat antibiotic resistance in general practice.

aimTo identify subgroups of UTI patients in which the use of urine cultures and antibiotic prescriptions deviates from the national guidelines.

methodsWe investigated associations of several characteristics with urine culture orders in patients with UTI in 2015 from seven Dutch general practices (n=1295). These included subgroups at risk for UTI complications, comorbidities, age and history of UTI recurrence. In addition, we assessed the level of adherence to the guideline for antibiotic prescriptions in subgroups at risks for UTI complications.

findingsUrine cultures were ordered in 17% (n=221) of patients, more frequently in high-risk patients (32%) than in low-risk patients (7%), for UTI complications (OR=6.4; 95% CI 4.6-9.0). In low-risk patients, 91% received antibiotics that were recommended in the guideline. For high-risk patients this percentage ranged widely, and was particularly low in the risk groups with signs of tissue invasion (29-50%). Diagnostic and therapeutic adequacy can still be improved by increasing the adherence to the guideline in UTI patients at high risk for complications. This may contribute to containing antibiotic resistance in UTI by ordering urine cultures and use the results to adjust prescriptions to antibiotic susceptibility of the uropathogen.

Indexed as

antibacterial agentsculturesdrug resistancegeneral practicemicrobialurinary tract infections

Identifiers

PMID30168406
PMCPMC6536752
OpenAlexW2889344724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.