Evidence map›Paper›PMID 30168356›Full record

Trial reportIntegrative cancer therapies2018

Osteopathic Manipulative Treatment Effect on Pain Relief and Quality of Life in Oncology Geriatric Patients: A Nonrandomized Controlled Clinical Trial.

Chiara Arienti, Teresa Bosisio, Silvia Ratti, Rossella Miglioli, Stefano Negrini

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Integrative cancer therapies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03142386 (Pain and Quality of Life Management in Oncology Geriatric Patients With Osteopathic Manipulative Treatment), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03142386 nacompletednot on this map

Pain and Quality of Life Management in Oncology Geriatric Patients With Osteopathic Manipulative Treatment: a Pilot Study

TypeinterventionalSponsorFondazione Don Carlo Gnocchi ETSRan2015 to 2016Enrolled23ConditionsGeriatric Oncology, Osteopathy in Other Diseases Classified ElsewhereArmsOsteopathic manipulative treatment, Physiotherapy
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Functional outcomes in oncology patients receiving chiropractic care: a retrospective chart review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chiara Arienti1 IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.ORCID 0000-0003-0787-6075
Teresa Bosisio2 SIOM-Scientific Institute of Osteopathic Medicine, Senago, Milan, Italy.
Silvia Ratti3 Istituto Superiore di Osteopatia, Milan, Italy.
Rossella Miglioli1 IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Stefano Negrini1 IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.ORCID 0000-0002-1878-2747
Don Carlo Gnocchi Foundation · ITIstituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of present study was to study the effect of osteopathic manipulation on pain relief and quality of life improvement in hospitalized oncology geriatric patients.

methodsA nonrandomized controlled clinical trial was performed in the Oncology Rehabilitation Unit, Milan, Italy, from September 2015 to March 2016. Twenty-three older cancer patients were enrolled and allocated in 2 experimental groups: the study group (OMT group, N = 12) underwent osteopathic manipulative treatment in addition to physiotherapy, and the control group (PT group, N = 12) underwent only physiotherapy. At enrollment (T0), 24 recruited oncology patients completed the sociodemographic forms and were evaluated for pain intensity and quality of life by an external examiner. All patients were revaluated every week (T1, T2, T3, and T4) for pain intensity and at the end of the study treatment (T4) for quality of life. A standard level of significance was set at α < .05.

resultsThe 2 groups did not significantly differ in age ( P = .682), body mass index ( P = .413), or gender ( P = 1). The osteopathic manipulative treatment added to physiotherapy produced a significant reduction in Numeric Rating Scale (NRS) scores both at T2 ( P = .004) and T4 ( P = .002). The difference in quality of life improvements between T0 and T4 was not statistically significant. NRS improved in the PT group at T4. Between-group analysis of NRS and quality of life with the Mann-Whitney test did not show any significant difference between the 2 treatments.

conclusionsOur study showed a significant improvement in pain relief and a nonsignificant improvement in quality of life in hospitalized geriatric oncology patients during osteopathic manipulative treatment.

trial registrationProtocol registered on Clinicaltrials.gov (NCT03142386).

Indexed as

AgedCancer PainFemaleHumansItalyMaleManipulation, OsteopathicNeoplasmsPain ManagementPain MeasurementPilot ProjectsQuality of LifeTreatment Outcomecancer survivorsclinicgeriatricsmalignancyosteopathic manipulative treatmentrehabilitation

Identifiers

PMID30168356
PMCPMC6247559
OpenAlexW2889339862

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.