Evidence map›Paper›PMID 30168080›Full record

ArticleMycopathologia2018

Immunohistochemical Cross-Reactivity Between Paracoccidioides sp. from Dolphins and Histoplasma capsulatum.

Godai Shumoto, Keiichi Ueda, Sayaka Yamaguchi, Takashi Kaneshima, Toshihiro Konno, Yoshie Terashima, Atsushi Yamamoto, Luciene A Nagashima, Eiko N Itano, Ayako Sano

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Godai ShumotoRyukyu Animal Medical Center, Yone 5-27, Tomigusuku, Okinawa, 901-0224, Japan.
Keiichi UedaOkinawa Churashima Foundation, Aza Ishikawa 888, Motobu-Cho, Kunigami-Gun, Okinawa, 905-0206, Japan.
Sayaka YamaguchiDepartment of Dermatology, Faculty of Medicine, University of the Ryukyus, Uehara, Nishihara, Nakagusuku-Gun, Okinawa, 903-0215, Japan.
Takashi KaneshimaRyukyu Animal Medical Center, Yone 5-27, Tomigusuku, Okinawa, 901-0224, Japan.
Toshihiro KonnoThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima, 890-0065, Japan.
Yoshie TerashimaThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima, 890-0065, Japan.
Atsushi YamamotoThe United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima, 890-0065, Japan.
Luciene A NagashimaInstitute of Technology of Parana, Rua Joao Americo de Oliveira, 330, Curitiba, Parana, 80030-060, Brazil.
Eiko N ItanoDepartment of Pathological Science, CCB, State University of Londrina, P.O. Box 6001, Londrina, PR, 86051-970, Brazil.
Ayako SanoRyukyu Animal Medical Center, Yone 5-27, Tomigusuku, Okinawa, 901-0224, Japan. aya_grimalkin@yahoo.co.jp.ORCID http://orcid.org/0000-0001-5240-4750
Kagoshima University · JPInstituto de Tecnologia do Paraná · BROkinawa Churashima Foundation · JPUniversidade Estadual de Londrina · BRUniversity of the Ryukyus · JP

Funding

JICA J17-50165
6 · The paper itself

Abstract

Paracoccidioidomycosis ceti is a cutaneous disease of cetaceans caused by uncultivated Paracoccidioides brasiliensis or Paracoccidioides spp. Serological cross-reactions between paracoccidioidomycosis ceti and paracoccidioidomycosis, paracoccidioidomycosis and histoplasmosis, and paracoccidioidomycosis and coccidioidomycosis have been reported before. The present study aimed to detect immunohistochemical cross-reaction between antibodies to Paracoccidioides sp. and Histoplasma capsulatum, and vice versa. Thirty murine sera, obtained from experimental infections of 6 isolates of H. capsulatum, were reacted with paraffin-embedded yeast-form cells of Paracoccidioides sp. derived from a case of paracoccidioidomycosis ceti in Japan. The murine sera were also reacted with human isolates of H. capsulatum yeast cells, with P. brasiliensis yeast cells, and with fungal cells of Coccidioides posadasii. Three dolphins' sera from cases of paracoccidioidomycosis ceti, two human sera from patients with paracoccidioidomycosis, and a serum from a healthy person with a history of coccidioidomycosis were used in order to determine that the tested fungal cells reacted properly. Sera derived from mice infected with an isolate of H. capsulatum reacted positively against yeast cells of Paracoccidioides sp., yeast cells of P. brasiliensis, and fungal cells of C. posadasii, while those derived from other strains were negative. The present study recorded for the first time the cross-reaction between the yeast cells of H. capsulatum and antibodies against Paracoccidioides spp., the yeast cells of Paracoccidioides sp. and antibodies against H. capsulatum, the yeast cells of Paracoccidioides sp. and antibodies against Coccidioides sp., and fungal cells of C. posadasii and antibodies against Paracoccidioides spp.

Indexed as

Cross ReactionsImmunohistochemistryAnimalsAntibodies, FungalDolphinsHistoplasmaHumansMiceParacoccidioidesParacoccidioidomycosisAntibodies, FungalCoccidioidomycosisCross-reactionHistoplasmosisParacoccidioidomycosisParacoccidioidomycosis ceti

Identifiers

PMID30168080
OpenAlexW2889473695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.