Evidence map›Paper›PMID 30168040›Full record

ArticleInflammation2019

Electro-acupuncture Pretreatment at Zusanli (ST36) Acupoint Attenuates Lipopolysaccharide-Induced Inflammation in Rats by Inhibiting Ca

Tao Chen, Yong Xiong, Man Long, Dan Zheng, Hui Ke, Jun Xie, Nina Yin, Zebin Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  19. CBS-Induced HEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tao ChenDepartment of Anatomy, School of Basic Medical Sciences, Hubei University of Chinese Medicine, 1 Huangjiahu West Road, Hongshan District, Wuhan, 430065, China.
Yong XiongCollege of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Man LongSchool of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Dan ZhengDepartment of Anatomy, School of Basic Medical Sciences, Hubei University of Chinese Medicine, 1 Huangjiahu West Road, Hongshan District, Wuhan, 430065, China.
Hui KeDepartment of Anatomy, School of Basic Medical Sciences, Hubei University of Chinese Medicine, 1 Huangjiahu West Road, Hongshan District, Wuhan, 430065, China.
Jun XieCollege of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Nina YinDepartment of Anatomy, School of Basic Medical Sciences, Hubei University of Chinese Medicine, 1 Huangjiahu West Road, Hongshan District, Wuhan, 430065, China. yinnina-hbtcm@hotmail.com.
Zebin ChenHubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Hubei University of Chinese Medicine, No. 1 Huangjiahu West Road, Hongshan District, Wuhan, 430065, China. chenzebin-hbtcm@outlook.com.
Hubei University of Chinese Medicine · CN

Funding

Health and Family Planning Commission of Hubei Province No. 2013Z-Z01Natural Science Foundation of Hubei Province of China No. 2015CFA096
6 · The paper itself

Abstract

In this study, we aimed to investigate the effect of electro-acupuncture (EA) pretreatment at zusanli (ST36) acupoint on lipopolysaccharide (LPS)-induced endotoxemic rat model and explore the underlying molecular mechanisms. Rats were treated with EA at ST36 for 7 days before being subjected to LPS. Two hours post-LPS, samples such as serum, local acupoint tissues, and spleens were collected and processed for investigations including cytokine production, cytosolic calcium (Ca

Indexed as

Acupuncture PointsAcupuncture TherapyAnimalsCalciumCytokinesInflammationLipopolysaccharidesNF-kappa BRatsReceptor, Cannabinoid, CB2Toll-Like Receptor 4CalciumCytokinesLipopolysaccharidesNF-kappa BReceptor, Cannabinoid, CB2Tlr4 protein, ratToll-Like Receptor 4calciumcannabinoid CB2 receptorelectro-acupunctureinflammationlipopolysaccharideTLR4/NF-κB signaling

Identifiers

PMID30168040
OpenAlexW2889170063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.