Evidence map›Paper›PMID 30168032›Full record

ArticleEating and weight disorders : EWD2020

Deficits in response inhibition on varied levels of demand load in anorexia nervosa: an event-related potentials study.

Ling Yue, Yingying Tang, Qing Kang, Qian Wang, Jijun Wang, Jue Chen

Abstract read
In one paragraph

Article in Eating and weight disorders : EWD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
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  8. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  9. Review
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ling YueDepartment of Clinical Psychology, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai, 200030, People's Republic of China.ORCID http://orcid.org/0000-0001-6476-0189
Yingying TangDepartment of EEG and Imaging, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai, 200030, People's Republic of China.
Qing KangDepartment of Clinical Psychology, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai, 200030, People's Republic of China.
Qian WangMed-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Jijun WangDepartment of EEG and Imaging, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai, 200030, People's Republic of China. jijunwang27@gmail.com.
Jue ChenDepartment of Clinical Psychology, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai, 200030, People's Republic of China. chenjue2088@163.com.

Funding

Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai 2017YQ069Natural Science Foundation of Shanghai 16ZR1430400Natural Science Foundation of Shanghai 17ZR1424700Science and Technology Commission of Shanghai Municipality 16411965200Shanghai Jiao Tong University YG2016MS36Shanghai Municipal Population and Family Planning Commission 20144Y0081Shanghai Municipal Population and Family Planning Commission 201640050the National Key Clinical Disciplines at Shanghai Mental Health Centre Office of Medical Affairs, Ministry of Health, 2011-873; OMA-MH, 2011-873the National Natural Science Foundation 81771461
6 · The paper itself

Abstract

purposeThe aim of the present study was to investigate the executive function of inhibitory control in anorexia nervosa (AN), which is considered as an underlying pathophysiology of restricting eating.

methodsIn this work, we examined the function of response inhibition in 27 unmedicated AN patients and 30 healthy controls (HC) using stop-signal tasks with different demand loads. Two event-related potentials (ERP) during the stop-signal tasks, N2 and P300, were compared between the AN and HC groups.

resultsWe found attenuated P300 amplitudes and delayed N2 latencies in AN patients across all three demand loads compared to HCs. We also found significant interaction between group and level of demand load. N2 latencies were prolonged when the inhibitory demand was lower in the AN group, whereas no differences in N2 latencies were found across different demand loads in HCs.

conclusionsTaken together, altered P300 amplitudes and N2 latencies may be associated with impaired response inhibition in AN patients. In particular, alterations of fronto-central N2 activations were demand-related, which might contribute to an aberrant inhibitory control process in AN. LEVEL OF EVIDENCE: Level II, controlled trial without randomization.

Indexed as

Inhibition, PsychologicalAdolescentAnorexia NervosaCase-Control StudiesElectroencephalographyEvent-Related Potentials, P300Evoked PotentialsFemaleHumansYoung AdultAnorexia nervosaEvent-related potentialsN2P300Response inhibition.Stop-signal task

Identifiers

PMID30168032
PMCPMC6997249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.