Evidence map›Paper›PMID 30167985›Full record

ArticleThe journal of headache and pain2018

Vascular wall imaging in reversible cerebral vasoconstriction syndrome - a 3-T contrast-enhanced MRI study.

Chun-Yu Chen, Shih-Pin Chen, Jong-Ling Fuh, Jiing-Feng Lirng, Feng-Chi Chang, Yen-Feng Wang, Shuu-Jiun Wang

Open access · goldAbstract read
In one paragraph

Article in The journal of headache and pain, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Idiopathic extracranial internal carotid artery vasospasm: case report and systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  2. MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
    Pooled it
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  11. Advances in Management of the Stroke Etiology One-Percenters.Current neurology and neuroscience reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chun-Yu ChenDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
Shih-Pin ChenDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan. chensp1977@gmail.com.ORCID http://orcid.org/0000-0003-3492-9902
Jong-Ling FuhDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
Jiing-Feng LirngFaculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
Feng-Chi ChangFaculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
Yen-Feng WangDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
Shuu-Jiun WangDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
National Yang Ming Chiao Tung University · TW

Funding

Academia Sinica IBMS-CRC103-P04Brain Research Center, National Yang-Ming University The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE)Ministry of Health and Welfare MOHW 103-TDU-B-211-113-003, MOHW 104-TDU-B-211-113-003, MOHW 105-TDU-B-211-113-003Ministry of Science and Technology, Taiwan MOST 106-2314-B-010 -019 -MY2, MOST 107-2321-B-010 -001 -, and MOST 104-2314-B-010 -071 -MY3Taipei Veterans General Hospital V100E6-001, VGHUST105-G7-1-1, V105C-127, V105E9-001-MY2-1, VTA105-V1-1-1Taipei Veterans General Hospital V106C-117
6 · The paper itself

Abstract

backgroundLimited histopathology studies have suggested that reversible cerebral vasoconstriction syndromes (RCVS) does not present with vascular wall inflammation. Previous vascular imaging studies have had inconsistent vascular wall enhancement findings in RCVS patients. The aim of this study was to determine whether absence of arterial wall pathology on imaging is a universal finding in patients with RCVS.

methodsWe recruited patients with RCVS from Taipei Veterans General Hospital prospectively from 2010 to 2012, with follow-up until 2017 (n = 48). We analyzed the characteristics of vascular wall enhancement in these patients without comparisons to a control group. All participants received vascular wall imaging by contrasted T1 fluid-attenuated inversion recovery with a 3-T magnetic resonance machine. The vascular wall enhancement was rated as marked, mild or absent.

resultsOf 48 patients with RCVS, 22 (45.8%) had vascular wall enhancement (5 marked and 17 mild). Demographics, clinical profiles, and cerebral artery flow velocities were similar across patients with versus without vascular wall enhancement, except that patients with vascular wall enhancement had fewer headache attacks than those without (p = 0.04). Follow-up imaging completed in 14 patients (median interval, 7 months) showed reduced enhancement in 9 patients, but persistent enhancement in 5.

conclusionAlmost half of our RCVS patients exhibited imaging enhancement of diseased vessels, and it was persistent for approximately a third of those patients with follow-up imaging. Both acute and persistent vascular wall enhancement may be unhelpful for differentiating RCVS from central nervous system vasculitis or subclinical atherosclerosis.

Indexed as

Contrast MediaMagnetic Resonance ImagingAdultCerebral AngiographyCerebral ArteriesCerebrovascular DisordersFemaleFollow-Up StudiesHeadache Disorders, PrimaryHumansImage EnhancementMagnetic Resonance AngiographyMaleMiddle AgedMuscle, Smooth, VascularPhlebographyContrast MediaContrast enhancementReversible cerebral vasoconstriction syndromesThunderclap headacheVascular wall imaging

Identifiers

PMID30167985
PMCPMC6117223
OpenAlexW2889389514

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.