Evidence map›Paper›PMID 30167981›Full record

ArticleMikrochimica acta2018

A glassy carbon electrode modified with a composite consisting of gold nanoparticle, reduced graphene oxide and poly(L-arginine) for simultaneous voltammetric determination of dopamine, serotonin and L-tryptophan.

Md Zaved H Khan, Xiaoqiang Liu, Yunfei Tang, Jinhua Zhu, Weiping Hu, Xiuhua Liu

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Md Zaved H KhanCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China.
Xiaoqiang LiuCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China.
Yunfei TangCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China.
Jinhua ZhuCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China.
Weiping HuCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China.
Xiuhua LiuCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China. ll514527@163.com.
Henan University · CN

Funding

National Natural Science Foundation of China U1204304
6 · The paper itself

Abstract

A glassy carbon electrode (GCE) was modified with poly(L-arginine) (P-Arg), reduced graphene oxide (rGO) and gold nanoparticle (AuNP) to obtain an electrode for simultaneous determination of dopamine (DA), serotonin (5-HT) and L-tryptophan (L-Trp) in the presence of ascorbic acid (AA). The modified GCE was prepared via subsequent 'layer-by-layer' deposition using an electrochemical technique. The surface morphology of the modified electrode was studied by scanning electron microscopy, and electrochemical characterizations were carried out via cyclic voltammetry and electrochemical impedance spectroscopy. The modified electrode showed excellent electrocatalytic activity toward DA, 5-HT and L-Trp at pH 7.0. Figures of merit for the differential pulse voltammetric reponse are as follows: (a) Response to DA is linear in two intervals, viz. 1.0-50 nM and 1.0-50 μM DA concentration range, the typical working voltage is 202 mV (vs. Ag/AgCl), and the detection limit is 1 nM (at an S/N ratio of 3). For 5-HT, the respective data are 10 to 500 nM and 1.0 to 10 μM, 381 mV, and 30 nM. For L-Trp, the respective data are 10-70 nM and 10-100 μM, 719 mV, and 0.1 μM. The modified GCE is fairly selective. It was successfully applied to the simultaneous determination of DA, 5-HT, and L-Trp in spiked urine samples, and high recovery rates were found. Graphical abstract Schematic presentation of the voltammetric sensor based on a glassy carbon electrode modified with poly(L-arginine), reduced graphene oxide (rGO) and gold nanoparticle (GCE/P-Arg/ErGO/AuNP) for simultaneous determination of dopamine (DA), serotonin (5-HT) and L-tryptophan (L-Trp).

Indexed as

CatalysisDopamineElectrochemistryGraphiteHumansMetal NanoparticlesModels, MolecularMolecular ConformationNanocompositesOxidation-ReductionOxidesPeptidesSerotoninTime FactorsTryptophanDopamineGraphiteOxidesPeptidespolyarginineSerotoninTryptophanCyclic voltammetryDifferential pulse voltammetryElectrochemical sensorNanocompositeScanning electron microscopy modified electrodeUrine analysis

Identifiers

PMID30167981
OpenAlexW2888968098

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.