Evidence map›Paper›PMID 30167914›Full record

ReviewNeurology and therapy2018

Practical Evidence-Based Recommendations for Patients with Multiple Sclerosis Who Want to Have Children.

Yara Dadalti Fragoso, Tarso Adoni, Joseph B Bidin Brooks, Alessandro Finkelsztejn, Paulo Diniz da Gama, Anderson K Grzesiuk, Vanessa Daccach Marques, Monica Fiuza K Parolin, Henry K Sato, Daniel Lima Varela and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neurology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Updated Perspectives on the Challenges of Managing Multiple Sclerosis During Pregnancy.Degenerative neurological and neuromuscular disease · 2022
    Review
  6. Review
  7. Disease Progression and Obstetric Outcomes of Women with Multiple Sclerosis at a Reference Center in Northeastern Brazil.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
    Article
  8. Article
  9. Article
  10. The road to conception for women with multiple sclerosis.Multiple sclerosis journal - experimental, translational and clinical
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Yara Dadalti FragosoUniversidade Metropolitana de Santos, Santos, SP, Brazil. yara@bsnet.com.br.
Tarso AdoniHospital Sirio-Libanes de Sao Paulo, São Paulo, SP, Brazil.
Joseph B Bidin BrooksUniversidade Metropolitana de Santos, Santos, SP, Brazil.
Alessandro FinkelsztejnHospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.
Paulo Diniz da GamaPontificia Universidade Católica Campus Sorocaba, Sorocaba, SP, Brazil.
Anderson K GrzesiukNeurologic Clinic in Cuiaba, Cuiabá, MT, Brazil.
Vanessa Daccach MarquesUniversidade de Sao Paulo Campus Ribeirao Preto, Ribeirão Prêto, SP, Brazil.
Monica Fiuza K ParolinNeurologic Clinic in Curitiba, Curitiba, PR, Brazil.
Henry K SatoInstituto de Neurologia de Curitiba, Curitiba, PR, Brazil.
Daniel Lima VarelaServico de Neurologia e Neurocirurgia, Passo Fundo, RS, Brazil.
Claudia Cristina F VasconcelosUniversidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Instituto de Neurologia de Curitiba · BRUniversidade Metropolitana de Santos · BRHospital de Clínicas de Porto Alegre · BRHospital Sírio-Libanês · BRUniversidade de Cuiabá · BRUniversidade de Ribeirão Preto · BRUniversidade de Sorocaba · BRUniversidade Federal do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) management presently aims to reach a state of no (or minimal) evidence of disease activity. The development and commercialization of new drugs has led to a renewed interest in family planning, since patients with MS may face a future with reduced (or no) disease-related neurological disability. The advice of neurologists is often sought by patients who want to have children and need to know more about disease control at conception and during pregnancy and the puerperium. When MS is well controlled, the simple withdrawal of drugs for patients who intend to conceive is not an option. On the other hand, not all treatments presently recommended for MS are considered safe during conception, pregnancy and/or breastfeeding. The objective of the present study was to summarize the practical and evidence-based recommendations for family planning when our patients (women and men) have MS.Funding TEVA Pharmaceutical Brazil.

Indexed as

Family planningMultiple sclerosisNeurologyPregnancyTherapy

Identifiers

PMID30167914
PMCPMC6283793
OpenAlexW2888796725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.