Evidence map›Paper›PMID 30167897›Full record

ArticleMikrochimica acta2018

Voltammetric immunoassay for Mycobacterium tuberculosis secretory protein MPT64 based on a synergistic amplification strategy using rolling circle amplification and a gold electrode modified with graphene oxide, Fe

Dan Gou, Guoming Xie, Yuxia Li, Xin Zhang, Hui Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Biosensors; nanomaterial-based methods in diagnosing ofJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Review
  4. Diverse applications and development of aptamer detection technology.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dan GouClinical Laboratories, The First Affiliated Hospital of Chongqing Medical University, No. 1, You Yi Road, Yu Zhong District, Chongqing, 400016, People's Republic of China.
Guoming XieKey Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Yuxia LiClinical Laboratories, The First Affiliated Hospital of Chongqing Medical University, No. 1, You Yi Road, Yu Zhong District, Chongqing, 400016, People's Republic of China.
Xin ZhangClinical Laboratories, The First Affiliated Hospital of Chongqing Medical University, No. 1, You Yi Road, Yu Zhong District, Chongqing, 400016, People's Republic of China.
Hui ChenClinical Laboratories, The First Affiliated Hospital of Chongqing Medical University, No. 1, You Yi Road, Yu Zhong District, Chongqing, 400016, People's Republic of China. huichen@hospital.cqmu.edu.cn.ORCID 0000-0001-5662-8700
The Affiliated Yongchuan Hospital of Chongqing Medical University · CNChongqing Medical University · CN

Funding

National Natural Science Foundation of China 81672112
6 · The paper itself

Abstract

The authors describe an electrochemical immunoassay for ultrasensitive determination of the Mycobacterium tuberculosis (MTb) secretory protein MPT64 which is an antigen for early diagnosis of infection with MTb. Protein G was used to immobilize antibodies against MPT64 on a gold electrode. Graphene oxide with its large surface area was used as a carrier to anchor magnetite (Fe

Indexed as

Nucleic Acid Amplification TechniquesAntigens, BacterialBiosensing TechniquesDNA ProbesElectrochemistryElectrodesGoldGraphiteHumansHydrogen-Ion ConcentrationImmunoassayLimit of DetectionMagnetite NanoparticlesMetal NanoparticlesModels, MolecularNanocompositesAntigens, BacterialDNA ProbesGoldGraphiteMagnetite NanoparticlesMPT64 protein, Mycobacterium tuberculosisPlatinumAptamer primerBiosensorCircular DNADifferential pulse voltammetryHorseradish peroxidaseMagnetiteMPT64NanocompositeProtein G

Identifiers

PMID30167897
OpenAlexW2889467056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.