ReviewPlant cell reports2018
Genome editing in diatoms: achievements and goals.
Review in Plant cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 59 citations in OpenAlex.
- Monogalactosyldiacylglycerol synthase isoforms play diverse roles inside and outside the diatom plastid.The Plant cell · 2024Article
- Microalgal biofilm induces larval settlement in the model marine wormRoyal Society open science · 2024Article
- Algicidal bacteria-derived membrane vesicles as shuttles mediating cross-kingdom interactions between bacteria and algae.Science advances · 2024Article
- Article
- Identification of promoter targets by Aureochrome 1a in the diatom Phaeodactylum tricornutum.Journal of experimental botany · 2024Article
- Integrated overview of stramenopile ecology, taxonomy, and heterotrophic origin.The ISME journal · 2024Review
- Targeted Gene Editing of Nuclear-Encoded Plastid Proteins in Phaeodactylum tricornutum via CRISPR/Cas9.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Microbial applications for sustainable space exploration beyond low Earth orbit.NPJ microgravity · 2023Review
- The first genetic engineered system for ovothiol biosynthesis in diatoms reveals a mitochondrial localization for the sulfoxide synthase OvoA.Open biology · 2023Article
- Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration.Nature communications · 2023Article
- Light-Driven Synthetic Biology: Progress in Research and Industrialization of Cyanobacterial Cell Factory.Life (Basel, Switzerland) · 2022Review
- Harnessing Solar Energy using Phototrophic Microorganisms: A Sustainable Pathway to Bioenergy, Biomaterials, and Environmental Solutions.Renewable & sustainable energy reviews · 2021Article
- Biochemical and Molecular Aspects of Phosphorus Limitation in Diatoms and Their Relationship with Biomolecule Accumulation.Biology · 2021Review
- Integrative omics identification, evolutionary and structural analysis of low affinity nitrate transporters in diatoms, diNPFs.Open biology · 2021Article
- Altering the Sex Pheromone Cyclo(l-Pro-l-Pro) of the DiatomInternational journal of molecular sciences · 2021Article
- An optimised method for intact nuclei isolation from diatoms.Scientific reports · 2021Article
- Identification of Loci Enabling Stable and High-Level Heterologous Gene Expression.Frontiers in bioengineering and biotechnology · 2021Article
- Multiplexed Genome EditingFrontiers in plant science · 2021Article
- A Metabolomics Exploration of the Sexual Phase in the Marine DiatomMarine drugs · 2020Article
- Diatom Molecular Research Comes of Age: Model Species for Studying Phytoplankton Biology and Diversity.The Plant cell · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 5 countries.
Funding
Abstract
Diatoms are major components of phytoplankton and play a key role in the ecology of aquatic ecosystems. These algae are of great scientific importance for a wide variety of research areas, ranging from marine ecology and oceanography to biotechnology. During the last 20 years, the availability of genomic information on selected diatom species and a substantial progress in genetic manipulation, strongly contributed to establishing diatoms as molecular model organisms for marine biology research. Recently, tailored TALEN endonucleases and the CRISPR/Cas9 system were utilized in diatoms, allowing targeted genetic modifications and the generation of knockout strains. These approaches are extremely valuable for diatom research because breeding, forward genetic screens by random insertion, and chemical mutagenesis are not applicable to the available model species Phaeodactylum tricornutum and Thalassiosira pseudonana, which do not cross sexually in the lab. Here, we provide an overview of the genetic toolbox that is currently available for performing stable genetic modifications in diatoms. We also discuss novel challenges that need to be addressed to fully exploit the potential of these technologies for the characterization of diatom biology and for metabolic engineering.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.