Evidence map›Paper›PMID 30167645›Full record

Observational studyJAMA cardiology2018

Trends in Hospice Discharge and Relative Outcomes Among Medicare Patients in the Get With The Guidelines-Heart Failure Registry.

Haider J Warraich, Haolin Xu, Adam D DeVore, Roland Matsouaka, Paul A Heidenreich, Deepak L Bhatt, Adrian F Hernandez, Clyde W Yancy, Gregg C Fonarow, Larry A Allen

Registry-linked trialOpen access · bronzeAbstract readObservational Study
In one paragraph

Observational study in JAMA cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03724695 (Advanced Heart Care at Home), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03724695 nacompletednot on this map

Advanced Heart Care at Home (AHCAH); a Pragmatic Randomized Trial for Clinicians Nudged to AHCAH, a Heart Failure Specific Home Palliative Care Services

TypeinterventionalSponsorUniversity of PennsylvaniaRan2018 to 2024Enrolled709ConditionsPalliative Care, Heart Failure, Health Care Utilization, Quality ImprovementArmsClinician nudge or opt out approach for AHCAH liaison visit
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Trends and Disparities in Palliative Care Encounters in Acute Heart Failure Admissions; Insight From National Inpatient Sample.Cardiovascular revascularization medicine : including molecular interventions · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Haider J WarraichDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Haolin XuDuke Clinical Research Institute, Durham, North Carolina.
Adam D DeVoreDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Roland MatsouakaDuke Clinical Research Institute, Durham, North Carolina.
Paul A HeidenreichDepartment of Medicine, Stanford University School of Medicine, Stanford, California.
Deepak L BhattDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Adrian F HernandezDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Clyde W YancyDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Gregg C FonarowDepartment of Medicine, University of California, Los Angeles.
Larry A AllenDepartment of Medicine, University of Colorado, Aurora.
Clinical Research Institute · USDuke Medical Center · USHarvard University · USNorthwestern University · USStanford University · USUniversity of California, Los Angeles · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: While 1 in 10 older patients hospitalized with heart failure (HF) die within 30 days, end-of-life care for this population is not well described. Objective: To assess rates of discharge to hospice, readmission after hospice, and survival in hospice in patients following hospital discharge. Design, Setting, and Participants: In this observational cohort analysis of patients in the multicenter American Heart Association Get With The Guidelines (GWTG)-HF registry linked to Medicare fee-for-service claims data, we analyzed patients 65 years and older discharged alive from the hospital between 2005 and 2014. We compared 4588 patients discharged to hospice with 4357 patients with advanced HF (ejection fraction ≤25% and any of the following: inpatient inotrope use, serum sodium level ≤130 mEq/L, blood urea nitrogen level ≥45 mg/dL [to convert to micromoles per liter, multiply by 0.357], systolic blood pressure ≤90 mm Hg, or comfort measures during hospitalization) not discharged to hospice and with 113 045 other patients with HF in the GWTG-HF registry. Data were analyzed from October 2017 to June 2018. Main Outcomes and Measures: Discharge to hospice, rehospitalization, and mortality. Results: Of the 4588 patients discharged to hospice, 2556 (55.7%) were female and 4047 (88.2%) were white, and they had a median (interquartile range) age of 86 (80-90) years. Hospice accounted for 4588 of 121 990 discharges (3.8%), of which 2424 (52.8%) were discharges to home hospice and 2164 (47.2%) were to a hospice facility. Hospice discharges increased from 2.0% (109 of 5528) in 2005 to 4.9% (968 of 19 590) in 2014. Patients discharged to hospice were older, white, and more symptomatic compared with patients with advanced HF (n = 4357) and other patients in the GWTG-HF registry (n = 113 045). The median (interquartile range) postdischarge survival time in patients discharged to hospice was 11 (3-63) days compared with 318 (78-1105) days in patients with advanced HF and 754 (221-1868) days in other patients in the GWTG-HF registry. A total of 739 patients (34.1%) discharged to hospice facilities died in less than 72 hours, while 295 (12.2%) discharged to home hospice died in less than 72 hours; 690 patients (15.0%) discharged from hospice lived for 6 months or more. Among hospitals with more than 25 hospice discharges, the median (interquartile range) hospice discharge rate was 3.5% (2.0%-5.7%). Readmission at 30 days was lower in patients discharged to hospice (189 [4.1%]) compared with patients with advanced HF (1185 [27.2%]) and others in the GWTG-HF registry (25 022 [22.2%]). Nonwhite race and younger age were the strongest predictors of readmission from hospice. Conclusions and Relevance: Hospice use has grown to about 4.9% of Medicare HF hospital discharges, with significant hospital-level variation. Almost a quarter of patients discharged to hospice die within 3 days of discharge, and about 4.1% of patients are readmitted to the hospital within 30 days.

Indexed as

AgedAged, 80 and overAge FactorsFemaleHeart FailureHospice CareHumansLength of StayMaleMedicarePatient DischargePatient ReadmissionRegistriesSurvival AnalysisUnited States

Identifiers

PMID30167645
PMCPMC6233829
OpenAlexW2889004866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.