Evidence map›Paper›PMID 30167574›Full record

ArticleSleep medicine and disorders : international journal2018

Obesity, obstructive sleep apnea and type 2 diabetes mellitus: Epidemiology and pathophysiologic insights.

Shazia Jehan, Alyson K Myers, Ferdinand Zizi, Seithikurippu R Pandi-Perumal, Girardin Jean-Louis, Samy I McFarlane

Open access · diamondAbstract read
In one paragraph

Article in Sleep medicine and disorders : international journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Guideline
  2. The relationship between obstructive sleep apnea and Parkinson's disease: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
  3. Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2019
    Guideline
  4. Trial
  5. Endoscopic lumbar decompression in patients with obesity does not correlate with inferior outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Development of a guide for continuous positive airway pressure use - A good fit: Making continuous positive airway pressure work for you.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2025
    Article
  13. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shazia JehanDepartment of Population Health, New York University School of Medicine, USA.
Alyson K MyersDepartment of Medicine, North Shore University Hospital, USA.
Ferdinand ZiziDepartment of Population Health, New York University School of Medicine, USA.
Seithikurippu R Pandi-PerumalSomnogen Canada Inc, Canada.
Girardin Jean-LouisDepartment of Population Health, New York University School of Medicine, USA.
Samy I McFarlaneDepartment of Medicine, SUNY Downstate Medical Center, USA.
SUNY Downstate Health Sciences University · US

Funding

Promoting Academic Workforce Development in Behavioral Medicine and Sleep Disorders ResearchR25HL105444 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Girardin Jean-Louis, Tatjana Rundek · 2010 to 2026
$5.8M
Tailored Peer-Based Sleep Health Education and Social Support in Blacks with OSAR01MD007716 · NIMHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JEAN-LOUIS, GIRARDIN, OGEDEGBE, OLUGBENGA G. · 2014 to 2018
$2.1M
Tailored Sleep Health Education: A Community-Engaged ApproachR25HL116378 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ALLEGRANTE, JOHN P., JEAN-LOUIS, GIRARDIN · 2013 to 2016
$1.0M
NHLBI NIH HHS R25 HL105444NHLBI NIH HHS R25 HL116378NIMHD NIH HHS R01 MD007716
6 · The paper itself

Abstract

Obesity is a major global health issue, and its prevalence is increasing. Obesity is associated with much comorbidity such as obstructive sleep apnea (OSA), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). Obesity is also one of the major causative factors of OSA, and OSA itself can promote the onset of after T2DM because hypoxic episodes decrease insulin sensitivity, and activation of the sympathetic pathway leads to the release of inflammatory markers associated with insulin resistance. Continuous Positive Airway Pressure (CPAP) can be used to ameliorate both conditions, as CPAP decreased hypoxia episodes and increases insulin sensitivity and improves glucose metabolism. Weight-loss strategies play an important role in improving OSA, T2DM, and other associated comorbidities. Lifestyle modification of diet and exercise, medications or bariatric surgery should be considered weight loss. The purpose of this review is to describe the relationship between obesity, OSA, and T2DM.

Indexed as

bariatric surgeryCPAPdiabetes mellitushyperglycaemiaobesityobstructive sleep apneaOSAT2DM

Identifiers

PMID30167574
PMCPMC6112821
OpenAlexW2896962617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.