Evidence map›Paper›PMID 30167506›Full record

ReviewJACC. Basic to translational science

The Role of the L-Type Ca

Helena M Viola, Victoria P A Johnstone, Henrietta Cserne Szappanos, Tara R Richman, Tatiana Tsoutsman, Aleksandra Filipovska, Christopher Semsarian, Jonathan G Seidman, Christine E Seidman, Livia C Hool

Open access · goldAbstract readReview
In one paragraph

Review in JACC. Basic to translational science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Novel Drug Targets in Diastolic Heart Disease.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
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  12. Characterization and validation of a preventative therapy for hypertrophic cardiomyopathy in a murine model of the disease.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Article
  15. Review
  16. The L-type CaChannels (Austin, Tex.) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Helena M ViolaSchool of Anatomy, Physiology and Human Biology, The University of Western Australia, Crawley, Australia.
Victoria P A JohnstoneSchool of Anatomy, Physiology and Human Biology, The University of Western Australia, Crawley, Australia.
Henrietta Cserne SzappanosSchool of Anatomy, Physiology and Human Biology, The University of Western Australia, Crawley, Australia.
Tara R RichmanThe Harry Perkins Institute for Medical Research, The University of Western Australia, Crawley, Australia.
Tatiana TsoutsmanAgnes Ginges Centre for Molecular Cardiology, Centenary Institute, Sydney, Australia.
Aleksandra FilipovskaThe Harry Perkins Institute for Medical Research, The University of Western Australia, Crawley, Australia.
Christopher SemsarianAgnes Ginges Centre for Molecular Cardiology, Centenary Institute, Sydney, Australia.
Jonathan G SeidmanHarvard Medical School, Harvard University, Boston, Massachusetts.
Christine E SeidmanHarvard Medical School, Harvard University, Boston, Massachusetts.
Livia C HoolSchool of Anatomy, Physiology and Human Biology, The University of Western Australia, Crawley, Australia.
University of Western Australia · AUCentenary Institute · AUHarvard University · USHarry Perkins Institute of Medical Research · AUVictor Chang Cardiac Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterozygous mice (

Indexed as

[Ca2+]i, intracellular calciumcalciumcardiomyopathyHCM, hypertrophic cardiomyopathyICa-L, L-type Ca2+ channelL-type calcium channelMHC, myosin heavy chainmitochondriaVDAC, voltage-dependent anion channelΨm, mitochondrial membrane potential

Identifiers

PMID30167506
PMCPMC6113168
OpenAlexW2309737132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.