ArticleScience advances2018
Hyperbolic geometry of the olfactory space.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state.eLife · 2026Article
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- Low rank adaptation of chemical foundation models generates effective odorant representations.bioRxiv : the preprint server for biology · 2026Article
- Grounding olfactory perception in language: Benchmarks and models for generating natural language odor descriptions.bioRxiv : the preprint server for biology · 2026Article
- Walks with jumps: a neurobiologically motivated class of paths in the hyperbolic plane.Journal of mathematical biology · 2026Article
- Integral Betti signatures of brain, climate and financial networks compared to hyperbolic, Euclidean and spherical models.Scientific reports · 2025Article
- Order code in the olfactory system.bioRxiv : the preprint server for biology · 2025Article
- Topological analysis of neuronal assemblies reveals low-rank structure modulated by cholinergic activity.bioRxiv : the preprint server for biology · 2025Article
- An Integrated Plasmonic Sensing Array for Chemical Fingerprinting and Flavor Profiling in Beverages and Other Liquids.ACS sensors · 2025Article
- Article
- Representational drift and learning-induced stabilization in the piriform cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Topological Neuroscience: Linking Circuits to Function.Annual review of neuroscience · 2025Review
- Article
- Olfactory Receptor Responses to Pure Odorants in Drosophila melanogaster.The European journal of neuroscience · 2025Article
- Representational geometry explains puzzling error distributions in behavioral tasks.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Adaptive data embedding for curved spaces.iScience · 2024Article
- DeepNose: An Equivariant Convolutional Neural Network Predictive Of Human Olfactory Percepts.ArXiv · 2024Article
- Tracking the topology of neural manifolds across populations.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The primacy model and the structure of olfactory space.PLoS computational biology · 2024Article
- ImAge quantitates aging and rejuvenation.Nature aging · 2024Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In the natural environment, the sense of smell, or olfaction, serves to detect toxins and judge nutritional content by taking advantage of the associations between compounds as they are created in biochemical reactions. This suggests that the nervous system can classify odors based on statistics of their co-occurrence within natural mixtures rather than from the chemical structures of the ligands themselves. We show that this statistical perspective makes it possible to map odors to points in a hyperbolic space. Hyperbolic coordinates have a long but often underappreciated history of relevance to biology. For example, these coordinates approximate the distance between species computed along dendrograms and, more generally, between points within hierarchical tree-like networks. We find that both natural odors and human perceptual descriptions of smells can be described using a three-dimensional hyperbolic space. This match in geometries can avoid distortions that would otherwise arise when mapping odors to perception.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.