Evidence map›Paper›PMID 30167240›Full record

ArticleLight, science & applications2017

Tomographic flow cytometry by digital holography.

Francesco Merola, Pasquale Memmolo, Lisa Miccio, Roberto Savoia, Martina Mugnano, Angelo Fontana, Giuliana D'Ippolito, Angela Sardo, Achille Iolascon, Antonella Gambale and 1 more

Open access · goldAbstract read
In one paragraph

Article in Light, science & applications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
27.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 392 citations in OpenAlex.

  1. Review
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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Francesco MerolaCNR-ISASI, Istituto di Scienze Applicate e Sistemi Intelligenti 'E. Caianiello', CNR-Consiglio Nazionale delle Ricerche, Pozzuoli 80078, Italy.
Pasquale MemmoloCNR-ISASI, Istituto di Scienze Applicate e Sistemi Intelligenti 'E. Caianiello', CNR-Consiglio Nazionale delle Ricerche, Pozzuoli 80078, Italy.
Lisa MiccioCNR-ISASI, Istituto di Scienze Applicate e Sistemi Intelligenti 'E. Caianiello', CNR-Consiglio Nazionale delle Ricerche, Pozzuoli 80078, Italy.
Roberto SavoiaCNR-ISASI, Istituto di Scienze Applicate e Sistemi Intelligenti 'E. Caianiello', CNR-Consiglio Nazionale delle Ricerche, Pozzuoli 80078, Italy.
Martina MugnanoCNR-ISASI, Istituto di Scienze Applicate e Sistemi Intelligenti 'E. Caianiello', CNR-Consiglio Nazionale delle Ricerche, Pozzuoli 80078, Italy.
Angelo FontanaCNR-ICB, Istituto di Chimica Biomolecolare, Pozzuoli 80078, Italy.
Giuliana D'IppolitoCNR-ICB, Istituto di Chimica Biomolecolare, Pozzuoli 80078, Italy.
Angela SardoCNR-ICB, Istituto di Chimica Biomolecolare, Pozzuoli 80078, Italy.
Achille IolasconDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II & CEINGE-Advanced Biotechnologies, Napoli 80145, Italy.
Antonella GambaleDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II & CEINGE-Advanced Biotechnologies, Napoli 80145, Italy.
Pietro FerraroCNR-ISASI, Istituto di Scienze Applicate e Sistemi Intelligenti 'E. Caianiello', CNR-Consiglio Nazionale delle Ricerche, Pozzuoli 80078, Italy.ORCID 0000-0002-0158-3856
Institute of Applied Science and Intelligent Systems · ITIstituto di Chimica Biomolecolare · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput single-cell analysis is a challenging task. Label-free tomographic phase microscopy is an excellent candidate to perform this task. However, in-line tomography is very difficult to implement in practice because it requires a complex set-up for rotating the sample and examining the cell along several directions. We demonstrate that by exploiting the random rolling of cells while they are flowing along a microfluidic channel, it is possible to obtain in-line phase-contrast tomography, if smart strategies for wavefront analysis are adopted. In fact, surprisingly,

Indexed as

microfluidicsred blood cellstomographic microscopywavefront analysis

Identifiers

PMID30167240
PMCPMC6062169
OpenAlexW2605076099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.