Evidence map›Paper›PMID 30166861›Full record

ArticleWorld journal of gastroenterology2018

C-peptide as a key risk factor for non-alcoholic fatty liver disease in the United States population.

Amporn Atsawarungruangkit, Jirat Chenbhanich, George Dickstein

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amporn AtsawarungruangkitDepartment of Medicine, MetroWest Medical Center, Framingham, MA 01702, United States.
Jirat ChenbhanichDepartment of Medicine, MetroWest Medical Center, Framingham, MA 01702, United States.
George DicksteinDepartment of Medicine, MetroWest Medical Center, Framingham, MA 01702, United States.
MetroWest Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine whether fasting C-peptide is an independent predictor for non-alcoholic fatty liver disease (NAFLD) in United States population.

methodsUsing the National Health and Nutrition Examination Survey (NHANES) 1988-1994, NAFLD participants aged 20 or greater without any other liver diseases were included in this study. Excessive alcohol intake is defined as > 2 drinks per day for males and > 1 drink per day for females. C-peptide and 27 other factors known to be associated with NAFLD (

resultsOf 18825 participants aged ≥ 20, 3235 participants (

conclusionTogether with waist circumference and ALT, fasting C-peptide is among three most important predictors of NAFLD in United States population in the NHANES data set. Further study is needed to validate the clinical utility of fasting C-peptide in diagnosis or monitoring insulin resistance in NAFLD patients.

Indexed as

Insulin ResistanceAdultAlanine TransaminaseCase-Control StudiesC-PeptideFastingFemaleHumansLiverLogistic ModelsMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseNutrition SurveysPrevalenceRisk FactorsAlanine TransaminaseC-PeptideC-peptideFatty liverHepatosteatosisInsulin resistanceMetabolic syndrome

Identifiers

PMID30166861
PMCPMC6113719
OpenAlexW2889380569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.