Evidence map›Paper›PMID 30166715›Full record

ArticleTransactions of the American Clinical and Climatological Association2018

THE CARDIOSPLENIC AXIS IS ESSENTIAL FOR THE PATHOGENESIS OF ISCHEMIC HEART FAILURE.

Sumanth D Prabhu

Open access · greenAbstract read
In one paragraph

Article in Transactions of the American Clinical and Climatological Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. CCR2Frontiers in pharmacology · 2026
    Article
  2. Immunometabolism in heart failure.Nature reviews. Cardiology · 2025
    Review
  3. CD206Circulation · 2025
    Article
  4. The spleen in ischaemic heart disease.Nature reviews. Cardiology · 2025
    Review
  5. Article
  6. Hypertrophic heart failure promotes gut dysbiosis and gut leakage in interleukin 10-deficient mice.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Circadian influence on the microbiome improves heart failure outcomes.Journal of molecular and cellular cardiology · 2020
    Article
  14. Inflammatory responses mediate brain-heart interaction after ischemic stroke in adult mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sumanth D PrabhuBIRMINGHAM, ALABAMA.

Funding

Splenic Marginal Zone Macrophages in Chronic Ischemic Heart FailureR01HL125735 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PRABHU, SUMANTH D · 2015 to 2018
$1.5M
Role of Regulatory T-Lymphocytes in Chronic Heart FailureI01BX002706 · VA · BIRMINGHAM VA MEDICAL CENTER · PI PRABHU, SUMANTH D · 2015 to 2018
–
BLRD VA I01 BX002706NHLBI NIH HHS R01 HL125735
6 · The paper itself

Abstract

The role of innate and adaptive immunity in heart failure (HF) is poorly understood. We discovered that mice with ischemic HF exhibit robust expansion of proinflammatory monocytes/macrophages, classical and plasmacytoid dendritic cells, and CD4

Indexed as

Adaptive ImmunityImmunity, InnateAnimalsCardiomyopathiesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDendritic CellsDisease Models, AnimalHeart FailureHumansImmunologic MemoryMacrophagesMonocytesMyocardial IschemiaMyocardiumSignal Transduction

Identifiers

PMID30166715
PMCPMC6116633
OpenAlexW2990521634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.