Evidence map›Paper›PMID 30166555›Full record

ArticleScientific reports2018

Vasopressin and oxytocin in sensory neurones: expression, exocytotic release and regulation by lactation.

Govindan Dayanithi, Oksana Forostyak, Serhiy Forostyak, Tomohiko Kayano, Yoichi Ueta, Alexei Verkhratsky

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  8. Influence of gap junctions upon CaBiophysics and physicobiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 6 countries.

Govindan DayanithiInstitut des Sciences Biologiques-Neurosciences, cognition, Centre Nationale de la Recherche Scientifique, 3 rue Michel-Ange, 75794, Paris cedex 16, France. gdaya@univ-montp2.fr.ORCID 0000-0002-1009-7809
Oksana ForostyakDepartment of Molecular Neurophysiology, Institute of Experimental Medicine, Czech Academy of Sciences, 14220, Prague, Czech Republic.
Serhiy ForostyakDepartment of Neuroscience, 2nd faculty of Medicine, Charles University, V Uvalu 84, 15006, Prague, Czech Republic.ORCID 0000-0001-5181-7756
Tomohiko KayanoMMDN-Institut National de la Santé et de la Recherche Médicale-U1198, Université de Montpellier, 34095, Montpellier, France.
Yoichi UetaDepartment of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, 807-8555, Japan.
Alexei VerkhratskyFaculty of Biology, Medicine and Health, University of Manchester, M13 9PT, Manchester, UK. Alexej.Verkhratsky@manchester.ac.uk.
École Pratique des Hautes Études · FRCharles University · CZCzech Academy of Sciences, Institute of Experimental Medicine · CZIkerbasque · ESUniversity of Occupational and Environmental Health Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurohormones arginine-vasopressin (AVP) and oxytocin (OT) synthesised in supraoptic and paraventricular nuclei of neurohypophysis regulate lactation, systemic water homeostasis and nociception. Using transgenic rats expressing AVP and OT tagged with fluorescent proteins we demonstrate that both neurohormones are expressed in sensory neurones both in vitro, in primary cultures, and in situ, in the intact ganglia; this expression was further confirmed with immunocytochemistry. Both neurohormones were expressed in nociceptive neurones immunopositive to transient receptor potential vannilloid 1 (TRPV1) channel antibodies. The AVP and OT-expressing DRG neurones responded to AVP, OT, 50 mM K

Indexed as

ExocytosisLactationAnimalsDehydrationFemaleFluorescenceGanglia, SpinalMaleNociceptionOxytocinPituitary Gland, PosteriorRats, TransgenicReceptors, OxytocinReceptors, VasopressinSensory Receptor CellsVasopressinsOxytocinReceptors, OxytocinReceptors, VasopressinVasopressins

Identifiers

PMID30166555
PMCPMC6117293
OpenAlexW2888756651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.