Evidence map›Paper›PMID 30166461›Full record

ArticleScience (New York, N.Y.)2018

Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water".

Gustavo Fuertes, Niccolo Banterle, Kiersten M Ruff, Aritra Chowdhury, Rohit V Pappu, Dmitri I Svergun, Edward A Lemke

Abstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Intrinsic stiffness andPNAS nexus · 2025
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  5. Review
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  8. Article
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  12. Review
  13. Article
  14. Commonly used FRET fluorophores promote collapse of an otherwise disordered protein.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Gustavo FuertesEuropean Molecular Biology Laboratory, 69117 Heidelberg, Germany.ORCID 0000-0002-8564-8644
Niccolo BanterleEuropean Molecular Biology Laboratory, 69117 Heidelberg, Germany.
Kiersten M RuffDepartment of Biomedical Engineering and Center for Biological Systems Engineering, Washington University, St. Louis, MO 63130, USA.ORCID 0000-0003-3240-1856
Aritra ChowdhuryEuropean Molecular Biology Laboratory, 69117 Heidelberg, Germany.
Rohit V PappuDepartment of Biomedical Engineering and Center for Biological Systems Engineering, Washington University, St. Louis, MO 63130, USA. edlemke@uni-mainz.de svergun@embl-hamburg.de pappu@wustl.edu.ORCID 0000-0003-2568-1378
Dmitri I SvergunEuropean Molecular Biology Laboratory, 22607 Hamburg, Germany. edlemke@uni-mainz.de svergun@embl-hamburg.de pappu@wustl.edu.ORCID 0000-0003-0830-5696
Edward A LemkeEuropean Molecular Biology Laboratory, 69117 Heidelberg, Germany. edlemke@uni-mainz.de svergun@embl-hamburg.de pappu@wustl.edu.ORCID 0000-0002-0634-0503

Funding

ROLE OF CHAIN LENGTH AND SEQUENCE CONTEXTS ON POLYGLUTAMINE OLIGOMERIZATIONR01NS056114 · NINDS · WASHINGTON UNIVERSITY · PI PAPPU, ROHIT V · 2007 to 2020
$4.4M
European Research Council 646451NINDS NIH HHS R01 NS056114
6 · The paper itself

Abstract

Editors at

Indexed as

Scattering, Small AngleX-Ray DiffractionHydrophobic and Hydrophilic InteractionsIntrinsically Disordered ProteinsProtein ConformationWaterIntrinsically Disordered ProteinsWater

Identifiers

PMID30166461
PMCPMC7611747

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.