Evidence map›Paper›PMID 30166431›Full record

ArticleAJNR. American journal of neuroradiology2018

Identification of Hostile Hemodynamics and Geometries of Cerebral Aneurysms: A Case-Control Study.

B J Chung, F Mut, C M Putman, F Hamzei-Sichani, W Brinjikji, D Kallmes, C M Jimenez, J R Cebral

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Investigation of Contrast Retention in PCOM Aneurysms as a Possible Marker for Instability and Rupture.International journal for numerical methods in biomedical engineering · 2026
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  6. Frontiers in bioengineering and biotechnology · 2024
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  11. Luminal enhancement in intracranial aneurysms: fact or feature?-A quantitative multimodal flow analysis.International journal of computer assisted radiology and surgery · 2021
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  15. Assessing the Risk of Intracranial Aneurysm Rupture Using Morphological and Hemodynamic Biomarkers Evaluated from Magnetic Resonance Fluid Dynamics and Computational Fluid Dynamics.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B J ChungFrom the Bioengineering and Mechanical Engineering Departments (B.J.C., F.M., J.R.C.), Volgenau School of Engineering George Mason University, Fairfax, Virginia.ORCID 0000-0002-5846-7944
F MutFrom the Bioengineering and Mechanical Engineering Departments (B.J.C., F.M., J.R.C.), Volgenau School of Engineering George Mason University, Fairfax, Virginia.ORCID 0000-0003-1907-3739
C M PutmanInterventional Neuroradiology Unit (C.M.P.), Inova Fairfax Hospital, Falls Church, Virginia.ORCID 0000-0001-5800-4686
F Hamzei-SichaniDepartment of Neurological Surgery (F.H.-S.), University of Massachusetts, Worcester, Massachusetts.ORCID 0000-0002-7688-9489
W BrinjikjiDepartment of Radiology (W.B., D.K.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-5271-5524
D KallmesDepartment of Radiology (W.B., D.K.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-8495-0040
C M JimenezNeurosurgery Department (C.M.J.), University of Antioquia, Medellin, Colombia.ORCID 0000-0002-1212-1446
J R CebralFrom the Bioengineering and Mechanical Engineering Departments (B.J.C., F.M., J.R.C.), Volgenau School of Engineering George Mason University, Fairfax, Virginia jcebral@gmu.edu.ORCID 0000-0002-3216-0856

Funding

Improved Evaluation of PCOM Aneurysms: Angio-Architecture, Hemodynamics and ShapeR21NS094780 · NINDS · GEORGE MASON UNIVERSITY · PI CEBRAL, JUAN R · 2015 to 2016
$407k
NINDS NIH HHS R21 NS094780
6 · The paper itself

Abstract

background and purposeHostile hemodynamic conditions and geometries are thought to predispose aneurysms for instability and rupture. This study compares stable, unstable, and ruptured aneurysms while controlling for location and patient characteristics. MATERIALS AND

methodsThe hemodynamics and geometries of 165 stable, 65 unstable, and 554 ruptured aneurysms were compared. Hemodynamics was modeled using image-based computational fluid dynamics. Case-control pairs were selected matching aneurysm location, patient age, and sex. Paired Wilcoxon tests were used to compare hemodynamic and geometric variables among different aneurysm groups. The pairing was repeated 100 times, and the combined

resultsRuptured aneurysms had lower minimum wall shear stress (

conclusionsUnstable and ruptured aneurysms have more complex flows with concentrated wall shear stress and are larger, more elongated, and irregular than stable aneurysms, independent of aneurysm location and patient sex and age.

Indexed as

AdultAgedAneurysm, RupturedCase-Control StudiesComputer SimulationFemaleHemodynamicsHumansHydrodynamicsIntracranial AneurysmMaleMiddle AgedRisk FactorsStress, Mechanical

Identifiers

PMID30166431
PMCPMC6177283

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.