Evidence map›Paper›PMID 30166079›Full record

ArticleAmerican journal of preventive medicine2018

Association Between Electronic Cigarette Use and Myocardial Infarction.

Talal Alzahrani, Ivan Pena, Nardos Temesgen, Stanton A Glantz

Erratum issued Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07009509 (Pilot and Feasibility Testing of a Peer-led Program to Prevent Youth Nicotine Vaping), which is not on this map. Cited by 195 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
195citing papers in PubMed, 10 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07009509 narecruitingnot on this mapstarted 2024, after this paper: background citation

Pilot and Feasibility Testing of a Peer-led Program to Prevent Youth Nicotine Vaping: The YES-CAN! Program

TypeinterventionalSponsorUniversity of Colorado, DenverRan2024 to 2026Enrolled1,166ConditionsNicotine VapingArmsYES-CAN! program
3 · Its place in the literature

Who cites it

195 citing papers in PubMed, 10 syntheses or guidelines pooled it, 355 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The prevalence of electronic cigarettes vaping globally: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2022
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Article
  14. Review
  15. Article
  16. Review
  17. E-cigarette use and Barrett's esophagus: evaluating a new risk in the era of vaping.Esophagus : official journal of the Japan Esophageal Society · 2026
    Article
  18. Article
  19. Review
  20. Article

135 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Talal AlzahraniDepartment of Medicine, George Washington University, Washington, District of Columbia.
Ivan PenaDepartment of Medicine, George Washington University, Washington, District of Columbia.
Nardos TemesgenDepartment of Medicine, George Washington University, Washington, District of Columbia.
Stanton A GlantzDepartment of Medicine, Cardiovascular Research Institute, Philip R. Lee Institute for Health Policy Studies, Center for Tobacco Control Research and Education, University of California, San Francisco, San Francisco, California. Electronic address: stanton.glantz@ucsf.edu.
George Washington University · USUniversity of California, San Francisco · US

Funding

Training and Education p489-500P50CA180890 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLANTZ, STANTON ARNOLD · 2013 to 2018
$20.5M
Effect of Tobacco Advocacy at the State LevelR01DA043950 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI APOLLONIO, DOROTHY ELINOR · 2016 to 2020
$2.6M
NCI NIH HHS P50 CA180890NIDA NIH HHS R01 DA043950
6 · The paper itself

Abstract

introductionElectronic cigarettes (e-cigarettes) are promoted as a less risky alternative to conventional cigarettes and have grown in popularity. Experimental and clinical evidence suggests that they could increase the risk of myocardial infarction.

methodsThe National Health Interview Surveys of 2014 (n=36,697) and 2016 (n=33,028) were used to examine the cross-sectional association between e-cigarette use (never, former, some days, daily) and cigarette smoking (same categories) and myocardial infarction in a single logistic regression model that also included demographics (age, gender, BMI) and health characteristics (hypertension, diabetes, and hypercholesterolemia) using logistic regression. Data were collected in 2014 and 2016 and analyzed in 2017 and 2018.

resultsDaily e-cigarette use was independently associated with increased odds of having had a myocardial infarction (OR=1.79, 95% CI=1.20, 2.66, p=0.004) as was daily conventional cigarette smoking (OR=2.72, 95% CI=2.29, 3.24, p<0.001). Former and some day e-cigarette use were not significantly associated with having had a myocardial infarction (p=0.608 and p=0.392) whereas former (OR=1.70, p<0.001) and some day cigarette smoking (OR=2.36, p<0.001) were. Odds of a myocardial infarction were also increased with history of hypertension (OR=2.32, p<0.001); high cholesterol (OR=2.36, p<0.001); and diabetes (OR=1.77, p<0.001); and age (OR=1.65 per 10 years, p<0.001). Women (OR=0.47, p<0.001) had lower odds of myocardial infarction.

conclusionsDaily e-cigarette use, adjusted for smoking conventional cigarettes as well as other risk factors, is associated with increased risk of myocardial infarction.

Indexed as

AdultCross-Sectional StudiesDiabetes MellitusElectronic Nicotine Delivery SystemsFemaleHumansHypertensionMaleMiddle AgedMyocardial InfarctionRisk FactorsSmokersSurveys and QuestionnairesUnited StatesVaping

Identifiers

PMID30166079
PMCPMC6208321
OpenAlexW2888590649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.