Evidence map›Paper›PMID 30165881›Full record

SynthesisJournal of orthopaedic surgery and research2018

Comparing the costs and outcomes of an integrated twin compression screw (ITCS) nail with standard of care using a single lag screw or a single helical blade cephalomedullary nail in patients with intertrochanteric hip fractures.

Leo M Nherera, Paul Trueman, Alan Horner, Alan J Johnstone, Tracy J Watson, Francis A Fatoye

Open access · goldAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Leo M NhereraHealth Economics, Smith & Nephew Global Market Access, 101 Hessle Road, Hull, HU3 2BN, UK. leo.nherera@smith-nephew.com.ORCID http://orcid.org/0000-0003-1758-9504
Paul TruemanHealth Economics, Smith & Nephew Global Market Access, 101 Hessle Road, Hull, HU3 2BN, UK.
Alan HornerHealth Economics, Smith & Nephew Global Market Access, 101 Hessle Road, Hull, HU3 2BN, UK.
Alan J JohnstoneUniversity of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, UK.
Tracy J WatsonOrthopedic and Spine Institute at Banner University Medical Center, Phoenix, AZ, USA.
Francis A FatoyeDepartment of Health Professions, Manchester Metropolitan University, Manchester, UK.
Smith & Nephew (United Kingdom) · GBBanner - University Medical Center Phoenix · USManchester Metropolitan University · GBSmith Institute · GBUniversity of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical treatment is the optimal strategy for managing intertrochanteric fractures as it allows for early rehabilitation and functional recovery. The purpose of the study was to assess the cost-effectiveness of commonly used cephalomedullary nails for the treatment of unstable intertrochanteric hip fractures.

methodsA decision analytic model was developed from a US payer's perspective using clinical data from a pairwise meta-analysis of randomised controlled trials (RCTs) and comparative observational studies comparing the integrated twin compression screw (ITCS) nail versus two single-screw or blade cephalomedullary nails [single lag screw (SLS) nail and single helical blade (SHB) nail]. The model considered a cohort of 1000 patients with a mean age of 76, as reported in the clinical studies over a 1-year time period. Cost data was obtained from the Center for Medicare and Medicaid Services website and published literature and adjusted for inflation. One-way and probabilistic sensitivity analyses were conducted to assess the effect of uncertainty in model parameters on model conclusions.

resultsThe model estimated 0.546 quality-adjusted life years (QALYs) and 0.78 complications avoided by using the ITCS nail and 0.455 QALYs and 0.67 complications avoided for the standard of care, using SLS or SHB nails. The cost per patient was $34,336 for patients treated with an ITCS nail and $37,036 for patients treated with the standard of care respectively, resulting in a cost saving of $2700 in favour of the ITCS nail. More savings were observed when the ITCS nail was compared to the SHB ($3280 per patient) and SLS ($1652 per patient). The findings were robust to a range of both one-way and the probabilistic sensitivity analyses.

conclusionIn conclusion, the ITCS nail can be considered a cost saving intervention in patients undergoing intertrochanteric fracture fixation with an intramedullary device. Clinicians and policy makers should be encouraged to adopt healthcare technologies such as ITCS that will help them to provide quality healthcare despite falling budgets.

Indexed as

Bone NailsBone ScrewsFracture Fixation, IntramedullaryHip FracturesAgedAged, 80 and overHumansRandomized Controlled Trials as TopicStandard of CareTreatment OutcomeCephalomedullary nailCost-effectiveness analysisIntegrated twin compression screwIntertrochanteric hip fracturesSingle helical blade screwSingle lag screw

Identifiers

PMID30165881
PMCPMC6117956
OpenAlexW2889403511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.