ArticleJournal of neurodevelopmental disorders2018
Neurophysiological correlates of holistic face processing in adolescents with and without autism spectrum disorder.
Article in Journal of neurodevelopmental disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Oxytocin impacts top-down and bottom-up social perception in adolescents with ASD: a MEG study of neural connectivity.Molecular autism · 2022Trial
- Neural oscillatory dynamics reveal altered top-down and integrative mechanisms during face processing in autistic children and unaffected siblings of autistic children.bioRxiv : the preprint server for biology · 2025Article
- Leveraging AI-Driven Neuroimaging Biomarkers for Early Detection and Social Function Prediction in Autism Spectrum Disorders: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Unveiling Face Recognition Challenges and Awareness in Autism Spectrum Disorder: Insights from the Italian Famous Face Test (IT-FFT).Journal of autism and developmental disorders · 2025Article
- Development and validation of the Interoceptive States Vocalisations (ISV) and Interoceptive States Point Light Displays (ISPLD) databases.Behavior research methods · 2025Article
- An Event-Related Potential Study on Facial Recognition in Children with and without Autism Spectrum Disorders.Neuropsychiatric disease and treatment · 2025Article
- Inferential Emotion Tracking reveals impaired context-based emotion processing in individuals with high Autism Quotient scores.Scientific reports · 2023Article
- Atypical oscillatory dynamics during emotional face processing in paediatric obsessive-compulsive disorder with MEG.NeuroImage. Clinical · 2023Article
- Atypically slow processing of faces and non-faces in older autistic adults.Autism : the international journal of research and practice · 2022Article
- High-level visual search in children with autism.Journal of vision · 2022Article
- The "Primitive Brain Dysfunction" Theory of Autism: The Superior Colliculus Role.Frontiers in integrative neuroscience · 2022Article
- Classification of evoked responses to inverted faces reveals both spatial and temporal cortical response abnormalities in Autism spectrum disorder.NeuroImage. Clinical · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundFace processing has been found to be impaired in autism spectrum disorders (ASD). One hypothesis is that individuals with ASD engage in piecemeal compared to holistic face processing strategies. To investigate the role of possible impairments in holistic face processing in individuals with autism, the current study investigated behavioral and electroencephalography (EEG) correlates of face processing (P1/N170 and gamma-band activity) in adolescents with ASD and sex-, age-, and IQ-matched neurotypical controls.
methodsParticipants were presented with upright and inverted Mooney stimuli; black and white low information faces that are only perceived as faces when processed holistically. Participants indicated behaviorally the detection of a face. EEG was collected time-locked to the presentation of the stimuli.
resultsAdolescents with ASD perceived Mooney stimuli as faces suggesting ability to use holistic processing but displayed a lower face detection rate and slower response times. ERP components suggest slowed temporal processing of Mooney stimuli in the ASD compared to control group for P1 latency but no differences between groups for P1 amplitude and at the N170. Increases in gamma-band activity was similar during the perception of the Mooney images by group, but the ASD group showed prolonged temporal elevation in activity.
conclusionOverall, our results suggest that adolescents with ASD were able to utilize holistic processing to perceive a face within the Mooney stimuli. Delays in early processing, marked by the P1, and elongated elevation in gamma activity indicate that the neural systems supporting holistic processing are slightly altered suggesting a less automatic and less efficient facial processing system.
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