Evidence map›Paper›PMID 30165664›Full record

ArticleThe Journal of infectious diseases2019

Serological Evidence of Japanese Encephalitis Virus Circulation in Asian Children From Dengue-Endemic Countries.

Joshua Nealon, Anne-Frieda Taurel, Sutee Yoksan, Annick Moureau, Matt Bonaparte, Luong Chan Quang, Maria R Capeding, Ari Prayitno, Sri Rezeki Hadinegoro, Danaya Chansinghakul and 1 more

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. NADFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  12. Essential Oils ofPlants (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joshua NealonSanofi Pasteur, Singapore.
Anne-Frieda TaurelSanofi Pasteur, Singapore.
Sutee YoksanMahidol University, Nakhonpathom, Thailand.
Annick MoureauSanofi Pasteur, Marcy L'Etoile, France.
Matt BonaparteSanofi Pasteur, Swiftwater, Pennsylvania.
Luong Chan QuangPasteur Institute Ho Chi Minh City, Vietnam.
Maria R CapedingResearch Institute for Tropical Medicine, Alabang, Muntinlupa City, Philippines.
Ari PrayitnoUniversitas of Indonesia, Jakarta.
Sri Rezeki HadinegoroUniversitas of Indonesia, Jakarta.
Danaya ChansinghakulSanofi Pasteur, Bangkok, Thailand.
Alain BouckenoogheSanofi Pasteur, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Japanese encephalitis virus (JEV) is a zoonotic, mosquito-borne flavivirus, distributed across Asia. Infections are mostly mild or asymptomatic, but symptoms include neurological disorders, sequelae, and fatalities. Data to inform control strategies are limited due to incomplete case reporting. Methods: We used JEV serological data from a multicountry Asian dengue vaccine study in children aged 2-14 years to describe JEV endemicity, measuring antibodies by plaque reduction neutralization test (PRNT50). Results: A total 1479 unvaccinated subjects were included. A minimal estimate of pediatric JEV seroprevalence in dengue-naive individuals was 8.1% in Indonesia, 5.8% in Malaysia, 10.8% in the Philippines, and 30.7% in Vietnam, translating to annual infection risks varying from 0.8% (in Malaysia) to 5.2% (in Vietnam). JEV seroprevalence and annual infection estimates were much higher in children with history of dengue infection, indicating cross-neutralization within the JEV PRNT50 assay. Conclusions: These data confirm JEV transmission across predominantly urban areas and support a greater emphasis on JEV case finding, diagnosis, and prevention.

Indexed as

AdolescentAsiaChildChild, PreschoolDengueDengue VaccinesDengue VirusEncephalitis, JapaneseEncephalitis Virus, JapaneseHumansIndonesiaMalaysiaNeutralization TestsPhilippinesPrevalenceSeroepidemiologic StudiesDengue Vaccines

Identifiers

PMID30165664
PMCPMC6325342

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.