ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019
Validation of a Claims-Based Frailty Index Against Physical Performance and Adverse Health Outcomes in the Health and Retirement Study.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers, 1 of them a synthesis that pooled it.
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Who cites it
207 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between oral frailty and physical frailty among older adults: a meta-analysis.BMC oral health · 2026Pooled it
- Effect of cerebellar vermis intermittent theta-burst stimulation on balance function in frail older adults: a randomized controlled trial.BMC geriatrics · 2026Trial
- Association Between Claims-Defined Frailty and Outcomes Following 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: Findings From the EXTEND-DAPT Study.Journal of the American Heart Association · 2023Trial
- Anticoagulation Outcomes in Nursing Home Residents With Atrial Fibrillation and ADL Disability.JAMA network open · 2026Article
- Complex or multivessel PCI is associated with higher 1-year mortality but better patient-centered outcomes when compared to CABG in patients with dementia.Journal of geriatric cardiology : JGC · 2026Article
- Form and function of actin impacts actin health and aging.iScience · 2026Article
- Frailty and low utilization of curative-intent surgical resection in nonmetastatic pancreatic cancer.JNCI cancer spectrum · 2026Article
- Frailty Is Associated With Postoperative Complications and Device Removal and Revision in Men Undergoing Surgery for Stress Urinary Incontinence.The Journal of urology · 2026Article
- Oral Anticoagulants in Patients With Atrial Fibrillation and Advanced CKD Not Requiring Dialysis.JAMA network open · 2026Article
- Dementia Is Associated With Adverse Outcomes After Nonruptured Abdominal Aortic Aneurysm Repair.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Incidence and Outcomes of Unplanned Intensive Interventions After Common Inpatient Surgeries: A Population-Based Cohort Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Claims-based frailty index and risk of hospitalisation for hip fracture among adults aged 60-74 years in Tokyo, Japan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Patterns of antithrombotic treatment after left atrial appendage occlusion.Heart rhythm · 2026Article
- Discontinuation of oral anticoagulants is common after catheter ablation in older patients with atrial fibrillation.European heart journal open · 2026Article
- Frailty and health resource utilization in 5450 adults with acute myeloid leukaemia: A population-based study from Ontario, Canada.British journal of haematology · 2026Article
- Clinical outcomes after antipsychotic discontinuation in nursing home residents with dementia: a nationwide cohort study.Alzheimer's research & therapy · 2026Article
- Administratively Defined Functional Vulnerability and Adverse Short-Term Outcomes in Older Adults Hospitalized with Crohn's Disease Flares: A Propensity-Matched Multicenter Cohort Study.Diseases (Basel, Switzerland) · 2026Article
- An Observational Study of Post-hip Fracture Outcomes in Older Adults with Type 2 Diabetes.Journal of general internal medicine · 2026Article
- Did frailty influence older adults' choices of communication methods during COVID-19?BMC geriatrics · 2026Article
- Longitudinal dynamics of post-diagnosis frailty among older women with ovarian cancer.Gynecologic oncology · 2026Article
147 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
Abstract
backgroundA claims-based frailty index (CFI) was developed based on a deficit-accumulation approach using self-reported health information. This study aimed to independently validate the CFI against physical performance and adverse health outcomes.
methodsThis retrospective cohort study included 3,642 community-dwelling older adults who had at least 1 health care encounter in the year prior to assessments of physical performance in the 2008 Health and Retirement Study wave. A CFI was estimated from Medicare claims data in the past year. Gait speed, grip strength, and the 2-year risk of death, institutionalization, disability, hospitalization, and prolonged (>30 days) skilled nursing facility (SNF) stay were evaluated for CFI categories (robust: <0.15, prefrail: 0.15-0.24, mildly frail: 0.25-0.34, moderate-to-severely frail: ≥0.35).
resultsThe prevalence of robust, prefrail, mildly frail, and moderate-to-severely frail state was 52.7%, 38.0%, 7.1%, and 2.2%, respectively. Individuals with higher CFI had lower mean gait speed (moderate-to-severely frail vs robust: 0.39 vs 0.78 m/s) and weaker grip strength (19.8 vs 28.5 kg). Higher CFI was associated with death (moderate-to-severely frail vs robust: 46% vs 7%), institutionalization (21% vs 5%), activity of daily living disability (33% vs 9%), instrumental activity of daily living disability (100% vs 22%), hospitalization (79% vs 23%), and prolonged SNF stay (17% vs 2%). The odds ratios per 1-SD (=0.07) difference in CFI were 1.46-2.06 for these outcomes, which remained statistically significant after adjustment for age, sex, and a comorbidity index.
conclusionThe CFI is useful to identify individuals with poor physical function and at greater risks of adverse health outcomes in Medicare data.
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