Evidence map›Paper›PMID 30165588›Full record

GuidelineEuropean heart journal. Cardiovascular pharmacotherapy2019

ESC Council on hypertension position document on the management of hypertensive emergencies.

Bert-Jan H van den Born, Gregory Y H Lip, Jana Brguljan-Hitij, Antoine Cremer, Julian Segura, Enrique Morales, Felix Mahfoud, Fouad Amraoui, Alexandre Persu, Thomas Kahan and 4 more

Erratum issuedOpen access · bronzeAbstract readPractice GuidelineReview
In one paragraph

Guideline in European heart journal. Cardiovascular pharmacotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 110 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 5 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 5 syntheses or guidelines pooled it, 282 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. [Integrated Care Protocol: Hypertension].Revista medica del Instituto Mexicano del Seguro Social · 2022
    Guideline
  4. Modern Management of Hypertensive Emergencies.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Pooled it
  5. Guideline
  6. Review
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Lipoprotein(a) in Essential Hypertension: Associations with Blood Pressure and Hypertension-Mediated Organ Damage.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Observational
  13. Article
  14. Article
  15. Review
  16. Treatment of Hypertensive Crisis in Primary Care Health Facilities in Peru, 2019-2024.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 10 countries.

Bert-Jan H van den BornDepartment of Internal Medicine, Division of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Gregory Y H LipInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.
Jana Brguljan-HitijHypertension Division, University Medical Centre Ljubljana, Department of Internal Medicine, Dr. Peter Držaj Hospital, Ljubljana, Slovenia.
Antoine CremerHypertension Unit, Department of Cardiology, Hopital Saint André and University Hospital of Bordeaux, Bordeaux, France.
Julian SeguraHypertension Unit, Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain.
Enrique MoralesHypertension Unit, Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain.
Felix MahfoudDepartment for Internal Medicine III, Cardiology, Angiology, and Intensive Care Medicine, Saarland University, Homburg/Saar, Germany.
Fouad AmraouiDepartment of Internal Medicine, Division of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Alexandre PersuDivision of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, and Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Thomas KahanKarolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Cardiovascular Medicine, Stockholm, Sweden.
Enrico Agabiti RoseiClinica Medica Generale, Department of Clinical and Experimental Sciences, University of Brescia, and Department of Medicine, Azienda Spedali Civili di Brescia, Brescia, Italy.
Giovanni de SimoneHypertension Research Center, Department of Translational Medical Sciences, Federico II University Hospital, Naples, Italy.
Philippe GosseHypertension Unit, Department of Cardiology, Hopital Saint André and University Hospital of Bordeaux, Bordeaux, France.
Bryan WilliamsUniversity College London (UCL) and UCL Hospitals, London, UK.
Academic Medical Center · NLHôpital Saint-André · FRResearch Institute Hospital 12 de Octubre · ESAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITFederico II University Hospital · ITKarolinska Institutet · SELjubljana University Medical Centre · SISaarland University · DEUCLouvain · BEUniversity College Hospital · GBUniversity of Birmingham · GB

Funding

Medical Research Council MC_PC_13090
6 · The paper itself

Abstract

Hypertensive emergencies are those situations where very high blood pressure (BP) values are associated with acute organ damage, and therefore, require immediate, but careful, BP reduction. The type of acute organ damage is the principal determinant of: (i) the drug of choice, (ii) the target BP, and (iii) the timeframe in which BP should be lowered. Key target organs are the heart, retina, brain, kidneys, and large arteries. Patients who lack acute hypertension-mediated end organ damage do not have a hypertensive emergency and can usually be treated with oral BP-lowering agents and usually discharged after a brief period of observation.

Indexed as

Antihypertensive AgentsBlood PressureConsensusDisease ProgressionEmergenciesHumansHypertensionRisk FactorsTreatment OutcomeAntihypertensive Agents

Identifiers

PMID30165588
PMCPMC13588668
OpenAlexW2888027923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.