ArticleAmerican journal of epidemiology2019
Pregnancy Outcomes in Women With Multiple Sclerosis.
Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-synthesis of the motherhood-related needs of women with multiple sclerosis.BMC women's health · 2024Pooled it
- Characterizing Perinatal Treatment Patterns and Outcomes in Myasthenia Gravis.Muscle & nerve · 2026Article
- Identifying multiple sclerosis in women of childbearing age in six European countries: a contribution from the ConcePTION project.European journal of epidemiology · 2025Article
- Multiple sclerosis, urinary tract infections and infertility: a comprehensive scoping review.Journal of the Turkish German Gynecological Association · 2025Article
- Pregnancy and Infant Outcomes in Women With Multiple Sclerosis Treated With Ocrelizumab.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Understanding the meaning of the lived experience "maternal role" in women with multiple sclerosis and planning a supportive program: a combined exploratory study protocol.Reproductive health · 2024Article
- Multiple Sclerosis and Family Planning: A Survey Study of the Patient Experience.Neurology. Clinical practice · 2024Article
- Pregnancy prevalence and outcomes after optic neuritis in South Korea.Scientific reports · 2023Article
- [Family planning in men and women with multiple sclerosis. Analysis of the Andalusian Registry (2018-2022)].Revista de neurologia · 2023Observational
- Multiple sclerosis, disease-modifying drugs and risk for adverse perinatal and pregnancy outcomes: Results from a population-based cohort study.Multiple sclerosis (Houndmills, Basingstoke, England) · 2023Article
- Assisted Reproductive Techniques in Multiple Sclerosis: Recommendations from an Expert Panel.Neurology and therapy · 2023Review
- Maternal Multiple Sclerosis and Health Outcomes Among the Children: A Systematic Review.Clinical epidemiology · 2023Review
- Stillbirth due to SARS-CoV-2 placentitis without evidence of intrauterine transmission to fetus: association with maternal risk factors.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Article
- Population-Based Study of Nonelective Postpartum Readmissions in Women With Stroke, Migraine, Multiple Sclerosis, and Myasthenia Gravis.Neurology · 2022Article
- Updated Perspectives on the Challenges of Managing Multiple Sclerosis During Pregnancy.Degenerative neurological and neuromuscular disease · 2022Review
- Impact ofNeurology. Clinical practice · 2021Article
- Data-Driven Modeling of Pregnancy-Related Complications.Trends in molecular medicine · 2021Review
- Pregnancy-Related and Perinatal Outcomes in Women With Multiple Sclerosis: A Nationwide Danish Cross-sectional Study.Neurology. Clinical practice · 2021Article
- Circulating endothelial progenitor cells during pregnancy in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- The Intersection of Disability and Pregnancy: Risks for Maternal Morbidity and Mortality.Journal of women's health (2002) · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Few studies have assessed the risk of adverse pregnancy outcomes in women with multiple sclerosis (MS). We used 2 large US administrative databases, the Truven Health MarketScan Database (2011-2015; Truven Health Analytics Inc., Ann Arbor, Michigan) and the Nationwide Inpatient Sample (2007-2011), to identify delivery cohorts. MS and pregnancy outcomes (infections, cesarean delivery, preterm delivery, poor fetal growth, preeclampsia, chorioamnionitis, postpartum hemorrhage, stillbirth, and infant malformations) were identified during pregnancy and at delivery. We calculated adjusted risk ratios according to MS status and relapse(s) in the year before delivery. Among over 5 million pregnancies, we identified 3,875 pregnancies in women with MS. Women with MS had an increased risk of infections during pregnancy (Truven Health: adjusted risk ratio (aRR) = 1.22, 95% confidence interval (CI): 1.16, 1.27) and preterm delivery (Truven Health: aRR = 1.19 (95% CI: 1.04, 1.35); Nationwide Inpatient Sample: aRR = 1.30 (95% CI: 1.16, 1.44)). The risks of other outcomes were similar for women with and without MS. In the Truven Health database, risk ratios for the pregnancy outcomes in women experiencing relapses versus those without relapses were between 0.9 and 1.4, and confidence intervals overlapped the null. Overall, women with MS had an increased risk of infections and preterm delivery; however, their risks for other adverse pregnancy outcomes were not elevated. Disease activity before delivery was not a strong predictor of outcomes.
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Registered trials
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