Evidence map›Paper›PMID 30165525›Full record

ArticleInflammatory bowel diseases2018

Development of a Sexual Dysfunction Scale for Women With Inflammatory Bowel Disease.

Punyanganie S de Silva, Aoibhlinn O'Toole, Linda G Marc, Christine A Ulysse, Marcia A Testa, Mette Julsgaard, Deanna Ngyuen, Ashwin Ananthakrishnan, Tine Laursen, Astrid Højgaard and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Inflammatory bowel diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

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  7. Associations with sexual dysfunction among a Canadian cohort with inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Punyanganie S de SilvaBrigham and Women's Hospital, Boston, Massachusetts.
Aoibhlinn O'TooleBrigham and Women's Hospital, Boston, Massachusetts.
Linda G MarcDepartment of Biostatistics, Harvard School of Public Health, Boston, Massachusetts.
Christine A UlysseDepartment of Biostatistics, Harvard School of Public Health, Boston, Massachusetts.
Marcia A TestaDepartment of Biostatistics, Harvard School of Public Health, Boston, Massachusetts.
Mette JulsgaardDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Deanna NgyuenMassachusetts General Hospital, Boston, Massachusetts.
Ashwin AnanthakrishnanMassachusetts General Hospital, Boston, Massachusetts.
Tine LaursenDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Astrid HøjgaardSexological Centre, Aalborg University Hospital, Aalborg, Denmark.
Lisbet A ChristensenDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Joshua KorzenikBrigham and Women's Hospital, Boston, Massachusetts.
Sonia FriedmanBrigham and Women's Hospital, Boston, Massachusetts.
Brigham and Women's Hospital · USAarhus University Hospital · DKHarvard University · USMassachusetts General Hospital · USAalborg University Hospital · DK

Funding

The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIMHD NIH HHS L60 MD002421NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Background: Women with inflammatory bowel disease (IBD) may have decreased sexual function. To understand how common this condition is in our female patients, we developed a new IBD-specific Female Sexual Dysfunction Scale (the IBD-FSDS). Methods: We performed a prospective cross-sectional study of 454 female IBD patients ≥18 years of age attending 1 of 3 IBD clinics in the United States or Denmark. We gathered information on sexual function via a de novo 23-item scale. General sexual functioning was measured with the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale-Revised (FSDS-R). Depressive symptoms were measured with the Patient Health Questionnaire-9 (PHQ-9). Medical history and sociodemographic data were collected via chart review. Exploratory factor analyses (EFAs) of the English language version of IBD-FSDS assessed unidimensionality, factor structure, reliability, criterion validity, and construct validity. Results: EFAs suggested retaining 15-items creating a unidimensional scale with strong internal consistency reliability (α = 0.93). Validity of the English language IBD-FSDS was measured using Spearman's coefficient, demonstrating significant criterion validity with the FSDS-R (P < 0.05) and the FSFI (P < 0.05) and significant construct validity with the composite for cases of active IBD (P < 0.05) and PHQ-9 (P < 0.05). Sexual dysfunction in women with IBD was significantly associated with depression (P = 0.042), active IBD (P = 0.002), and no history of surgery (P = 0.044). Conclusions: We have developed and validated an IBD-specific scale to assess the psychosexual impact of IBD in women. This novel screening questionnaire may help health care providers recognize factors contributing to impaired sexual function in their female patients.

Indexed as

AdultCross-Sectional StudiesFemaleFollow-Up StudiesHumansInflammatory Bowel DiseasesPrognosisProspective StudiesPsychometricsSeverity of Illness IndexSexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalSurveys and QuestionnairesWomen's Health

Identifiers

PMID30165525
PMCPMC6185125
OpenAlexW2809610058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.