ArticleAge and ageing2018
New horizons in the compression of functional decline.
Article in Age and ageing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Sarcopenia interventions in long-term care facilities targeting sedentary behaviour and physical inactivity: A systematic review.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Physical Activity in Community-Dwelling Older Adults: Which Real-World Accelerometry Measures Are Robust? A Systematic Review.Sensors (Basel, Switzerland) · 2023Pooled it
- Pooled it
- Effect of Multicomponent Intervention on Functional Decline in Chinese Older Adults: A Multicenter Randomized Clinical Trial.The journal of nutrition, health & aging · 2023Trial
- The Association Between Family Health and Proactive Health Risk Management With the Mediating Role of Health Literacy: Nationwide Cross-Sectional Study.JMIR public health and surveillance · 2026Article
- Physical fitness trends and factors influencing them in community-dwelling older adults: a longitudinal cohort study involving multiple tests.BMC geriatrics · 2025Article
- Community-based physical and social activity for older adults with mild frailty: a rapid qualitative study of a collaborative intervention pilot.BMC geriatrics · 2024Article
- Tree-based analysis of longevity predictors and their ten-year changes: a 35-Year mortality follow-up.BMC geriatrics · 2024Article
- Predictors of increasing disability in activities of daily living among people with advanced respiratory disease: a multi-site prospective cohort study, England UK.Disability and rehabilitation · 2024Article
- Does polypharmacy shape dependency transitions in the very old? Findings from the Newcastle 85+ Study.Age and ageing · 2022Article
- Projections of dependency and associated social care expenditure for the older population in England to 2038: effect of varying disability progression.Age and ageing · 2022Article
- Optimising function and well-being in older adults: protocol for an integrated research programme in Aotearoa/New Zealand.BMC geriatrics · 2022Article
- Resistance exercise training at different loads in frail and healthy older adults: A randomised feasibility trial.Experimental gerontology · 2021Article
- Transitions between levels of dependency among older people receiving social care - a retrospective longitudinal cohort study in a Swedish municipality.BMC geriatrics · 2021Article
- "What? That's for Old People, that." Home Adaptations, Ageing and Stigmatisation: A Qualitative Inquiry.International journal of environmental research and public health · 2019Article
- Latent class analysis identifies functional decline with Amsterdam IADL in preclinical Alzheimer's disease.Alzheimer's & dementia (New York, N. Y.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Population ageing, which has come about through the combination of increases in life expectancy, larger post-war cohorts reaching older age and reductions in fertility, is challenging societies and particularly health and care providers, worldwide. In Europe, the USA and Japan, there have been increases in years spent with disability and dependency. The majority of such research, as well as professional health and social care practice, measures loss of functional capability or need for social care, by aggregate disability scores, based around activities of daily living and instrumental activities of daily living. Although useful for defining whether an individual has passed a threshold, aggregate scores obscure how functional decline unfolds, and therefore where early intervention might improve intrinsic capacity and reverse or slow down decline, or maintain function. We propose a framework, the compression of functional decline (CFD), based on the latest understanding of the hierarchy of age-related functional decline, which has the potential to (i) help people understand how to live better for longer, (ii) allow the various stakeholders to be able to measure, at a population level, whether that is happening and (iii) identify which interventions are most effective at which stages. CFD is coherent with the World Health Organisation's Healthy Ageing model and is more easily understood by stakeholders and older people themselves, than current indicators such as frailty. CFD thus provides a realistic view of age-related functional decline in the context of modifiable behaviour to counter widespread public misconceptions about ageing and inform improvements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.