Evidence map›Paper›PMID 30161231›Full record

ArticlePLoS pathogens2018

Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?

David R Martinez, Genevieve G Fouda, Xinxia Peng, Margaret E Ackerman, Sallie R Permar

Open access · goldAbstract read
In one paragraph

Article in PLoS pathogens, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Maternal HIV infection drives altered placentalFrontiers in microbiology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Congenital Human Cytomegalovirus Infection Is Associated With Decreased Transplacental IgG Transfer Efficiency Due to Maternal Hypergammaglobulinemia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  16. Viral Infections During Pregnancy: The Big Challenge Threatening Maternal and Fetal Health.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

David R MartinezDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.
Genevieve G FoudaDuke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.ORCID 0000-0002-0960-1019
Xinxia PengBioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America.
Margaret E AckermanThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, United States of America.ORCID 0000-0002-4253-3476
Sallie R PermarDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.
Duke Medical Center · USDartmouth College · USNorth Carolina State University · US

Funding

International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) GroupU01AI068632 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI JACKSON, J BROOKS · 2006 to 2010
$109.7M
Project 2: RNA vaccination in early life to induce potent and broad HIV Env-specific antibody responsesP01AI117915 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE PARIS, KRISTINA, PERMAR, SALLIE R. · 2015 to 2024
$21.2M
Transmission-blocking potential of novel HIV Env-specific mucosal antibodiesR01AI106380 · NIAID · DUKE UNIVERSITY · PI PERMAR, SALLIE R. · 2013 to 2017
$3.4M
Maternal immune protection against congenital CMV infectionDP2HD075699 · NICHD · DUKE UNIVERSITY · PI PERMAR, SALLIE R. · 2012 to 2017
$2.8M
Role of neutralizing antibodies in HIV-1-infected and vaccinated mothers in MTCTR01AI122909 · NIAID · DUKE UNIVERSITY · PI KUMAR, AMIT · 2016 to 2019
$2.6M
NIAID NIH HHS P01 AI117915NIAID NIH HHS R01 AI106380NIAID NIH HHS R01 AI122909NIAID NIH HHS U01 AI068632NICHD NIH HHS DP2 HD075699
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsFemaleHumansImmunoglobulin GMaternal-Fetal ExchangePlacentaPregnancyReceptors, FcImmunoglobulin GReceptors, Fc

Identifiers

PMID30161231
PMCPMC6117057
OpenAlexW2889399576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.