Evidence map›Paper›PMID 30160595›Full record

ArticlePulmonary circulation

Sevoflurane inhibits cardiac function in pulmonary fibrosis mice through the TLR4 signaling pathway.

Yanan Cao, Zhenghua He, Maoen Zhu, Xiaowei Gao, Yue Yang, Junjie Zhang, Yundan Pan, Qulian Guo, Yonggang Peng, E Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yanan Cao1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhenghua He1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Maoen Zhu1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xiaowei Gao1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yue Yang1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Junjie Zhang1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yundan Pan1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qulian Guo1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yonggang Peng2 Department of Anesthesiology, Shands Hospital, University of Florida, Gainesville, FL, USA.
E Wang1 Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xiangya Hospital Central South University · CNCentral South University · CNUF Health Shands Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary fibrosis is often concomitant with myocardial injury. We studied sevoflurane's effects on cardiac function and the expression of the TLR4/inducible nitric oxide synthase (iNOS) signaling pathway on a pulmonary fibrosis model. C57BL/6J wild-type (WT) and TLR4-deficient (TLR4

Indexed as

cardiac functionpulmonary fibrosissevofluraneTLR4

Identifiers

PMID30160595
PMCPMC6134497
OpenAlexW2888973053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.