Evidence map›Paper›PMID 30159788›Full record

ArticleBreast cancer research and treatment2018

Obesity and mortality after locoregional breast cancer diagnosis.

A Holliston Moore, Amy Trentham-Dietz, Marguerite Burns, Ronald E Gangnon, Caprice C Greenberg, David J Vanness, John Hampton, Xiao-Cheng Wu, Roger T Anderson, Joseph Lipscomb and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Breast cancer research and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Obesity and high neutrophil-to-lymphocyte ratio are prognostic factors in non-metastatic breast cancer patients.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 1 country.

A Holliston MooreDepartment of Population Health Sciences, University of Wisconsin, Madison, WI, USA. ahmoore2@wisc.edu.ORCID http://orcid.org/0000-0003-0596-2711
Amy Trentham-DietzDepartment of Population Health Sciences, University of Wisconsin, Madison, WI, USA.
Marguerite BurnsDepartment of Population Health Sciences, University of Wisconsin, Madison, WI, USA.
Ronald E GangnonDepartment of Population Health Sciences, University of Wisconsin, Madison, WI, USA.
Caprice C GreenbergDepartment of Surgery, University of Wisconsin, Madison, WI, USA.
David J VannessDepartment of Health Policy and Administration, The Pennsylvania State University, University Park, PA, USA.
John HamptonUniversity of Wisconsin Paul P. Carbone Comprehensive Cancer Center, Madison, WI, USA.
Xiao-Cheng WuLouisiana State University Health Sciences Center, New Orleans, LA, USA.
Roger T AndersonUniversity of Virginia School of Medicine, Charlottesville, VA, USA.
Joseph LipscombRollins School of Public Health and Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Gretchen G KimmickDuke University Medical Center, Durham, NC, USA.
Rosemary CressPublic Health Institute, Cancer Registry of Greater California, Sacramento, USA.
J Frank WilsonMedical College of Wisconsin, Milwaukee, WI, USA.
Susan A SabatinoCenters for Disease Control and Prevention, Atlanta, GA, USA.
Steven T FlemingUniversity of Kentucky College of Public Health, Lexington, KY, USA.
University of Wisconsin–Madison · USCenters for Disease Control and Prevention · USDuke Medical Center · USEmory University · USLouisiana State University Health Sciences Center New Orleans · USMedical College of Wisconsin · USPennsylvania State University · USPublic Health Institute · USUniversity of Kentucky · USUniversity of Virginia · USUniversity of Wisconsin Carbone Cancer Center · USWisconsin Alumni Research Foundation · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Statistical Data Enclave CoreP30AG017266 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Michal Engelman · 1999 to 2026
$17.0M
Wisconsin Cancer Registry Evaluation: Patterns of Care StudyU01DP000261 · DP · MEDICAL COLLEGE OF WISCONSIN · PI WILSON, JESSE FRANK · 2005 to 2009
$716k
Centers for Disease Control and Prevention U01DP000261National Institutes of Health P50 CA14520NCCDPHP CDC HHS U01 DP000261NCI NIH HHS P30 CA014520NIA NIH HHS P30 AG017266
6 · The paper itself

Abstract

purposeHigher mortality after a breast cancer diagnosis has been observed among women who are obese. We investigated the relationships between body mass index (BMI) and all-cause or breast cancer-specific mortality after a diagnosis of locoregional breast cancer.

methodsWomen diagnosed in 2004 with AJCC Stage I, II, or III breast cancer (n = 5394) were identified from a population-based National Program of Cancer Registries (NPCR) patterns of care study (POC-BP) drawing from registries in seven U.S. states. Differences in overall and breast cancer-specific mortality were investigated using Cox proportional hazards regression models adjusting for demographic and clinical covariates, including age- and stage-based subgroup analyses.

resultsIn women 70 or older, higher BMI was associated with lower overall mortality (HR for a 5 kg/m

conclusionsContrary to our hypothesis, greater BMI was not associated with higher overall mortality. Among older women, BMI was inversely related to overall mortality, with a null association among younger women. Higher BMI was associated with breast cancer mortality among women with Stage I disease, but not among women with more advanced disease.

Indexed as

AdultAgedAged, 80 and overBody Mass IndexBreast NeoplasmsFemaleHumansMiddle AgedNeoplasm StagingObesityProportional Hazards ModelsAll-cause mortalityBreast cancerBreast cancer mortalityObesity

Identifiers

PMID30159788
PMCPMC6613372
OpenAlexW2888910755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.