Evidence map›Paper›PMID 30159655›Full record

ArticleHeart and vessels2019

Complete and incomplete revascularization in non-ST segment myocardial infarction with multivessel disease: long-term outcomes of first- and second-generation drug-eluting stents.

Ming-Jer Hsieh, Chun-Chi Chen, Cheng-Hung Lee, Chao-Yung Wang, Shang-Hung Chang, Dong-Yi Chen, Chia-Hung Yang, Ming-Lung Tsai, Jih-Kai Yeh, Ming-Yun Ho and 1 more

Abstract read
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In one paragraph

Article in Heart and vessels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ming-Jer HsiehDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Chun-Chi ChenDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Cheng-Hung LeeDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Chao-Yung WangDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Shang-Hung ChangDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Dong-Yi ChenDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Chia-Hung YangDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Ming-Lung TsaiDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Jih-Kai YehDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
Ming-Yun HoDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan.
I-Chang HsiehDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 5 Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan. a12390@cgmh.org.tw.ORCID http://orcid.org/0000-0002-0148-8357

Funding

Chang Gung Medical Foundation CORPG 3C0162Chang Gung Medical Foundation CORPG 3G0281
6 · The paper itself

Abstract

The therapeutic effects of reperfusion strategies with complete revascularization (CR) or incomplete revascularization (IR) in non-ST segment myocardial infarction (NSTEMI) patients with multivessel disease (MVD) are controversial. In such patients, whether utilization of different generations of drug-eluting stents (DES) for IR or CR affect long-term major adverse cardiovascular events (MACE) is unknown. This study included 702 NSTEMI patients with MVD who received first-generation (1G) or second-generation (2G) DES. In multivariable analysis, chronic kidney disease, chronic total, 1G DES and IR were independent predictors of long-term MACE. In patients receiving 1G DES, no significant differences of MACE were observed between the IR and CR groups (39.1% vs. 36.2%, p = 0.854). However, in patients receiving 2G DES, significantly fewer MACE were observed in the CR group than in the IR group (3.7% vs. 10.2%, p = 0.002). Compared with patients receiving 1G DES for IR, those receiving 2G DES for IR and CR exhibited significantly lower risk of MACE (59% and 83% lower, respectively). CR could not provide clinical benefits over IR in NSTEMI patients with MVD receiving 1G DES. However, in patients receiving 2G DES, compared with IR, CR was associated with a lower risk of long-term MACE, which was mainly caused by low rates of non-TLR and any revascularization.

Indexed as

Drug-Eluting StentsRegistriesCoronary AngiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedNon-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionProsthesis DesignTime FactorsTreatment OutcomeComplete revascularizationDrug-eluting stentsFirst generationNon-ST segment myocardial infarctionSecond generation

Identifiers

PMID30159655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.