Evidence map›Paper›PMID 30159333›Full record

Observational studyJournal of diabetes research2018

Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes.

Theresa van Gemert, Wolfgang Wölwer, Katharina S Weber, Annika Hoyer, Klaus Strassburger, Nora T Bohnau, Marie A Brüggen, Katharina Ovelgönne, Eva-Maria Gössmann, Volker Burkart and 4 more

Registry-linked trialAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01055093 (Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01055093 recruitingnot on this map

Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients

TypeobservationalSponsorGerman Diabetes CenterRan2005 to 2040Enrolled2,000ConditionsDiabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Review
  6. The Relation of Diabetes to Memory Function.Current neurology and neuroscience reports · 2020
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Theresa van GemertDivision of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-5121-3549
Wolfgang WölwerDepartment of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-7642-6778
Katharina S WeberInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-5731-4009
Annika HoyerGerman Center for Diabetes Research (DZD), Neuherberg, München, Germany.ORCID 0000-0002-0241-9951
Klaus StrassburgerGerman Center for Diabetes Research (DZD), Neuherberg, München, Germany.
Nora T BohnauInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-8928-2504
Marie A BrüggenInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-5532-2408
Katharina OvelgönneInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany.
Eva-Maria GössmannInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-8755-5428
Volker BurkartInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany.
Julia SzendroediDivision of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Michael RodenDivision of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Karsten MüssigDivision of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0003-0107-1196
GDS Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo test whether cognitive function is impaired in early states of diabetes and to identify possible risk factors for cognitive impairment.

methodsA cross-sectional analysis within the German Diabetes Study included patients with type 1 or type 2 diabetes within the first year after diagnosis or five years after study inclusion and metabolically healthy individuals. Participants underwent comprehensive metabolic phenotyping and testing of different domains of cognitive function. Linear regression models were used to compare cognition test outcomes and to test associations between cognitive function and possible influencing factors within the groups.

resultsIn participants with recently diagnosed diabetes, verbal memory was poorer in patients with type 2 diabetes (

conclusionVerbal memory is impaired in individuals with recently diagnosed type 2 diabetes and likely associated with higher body mass. This trial is registered with the trial registration number NCT01055093.

Indexed as

CognitionAdultAgedBiomarkersBlood GlucoseBody Mass IndexCognition DisordersC-PeptideCross-Sectional StudiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleGermanyGlycated HemoglobinHumansIntelligenceBiomarkersBlood GlucoseC-PeptideGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID30159333
PMCPMC6109580

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.