Evidence map›Paper›PMID 30159315›Full record

ArticleFrontiers in cardiovascular medicine2018

Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves.

Sylvia Dekker, Daphne van Geemen, Antoon J van den Bogaerdt, Anita Driessen-Mol, Elena Aikawa, Anthal I P M Smits

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sylvia DekkerSoft Tissue Engineering & Mechanobiology Division, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
Daphne van GeemenSoft Tissue Engineering & Mechanobiology Division, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
Antoon J van den BogaerdtDivision Heart Valve Bank, ETB-BISLIFE, Beverwijk, Netherlands.
Anita Driessen-MolSoft Tissue Engineering & Mechanobiology Division, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
Elena AikawaDivision of Cardiovascular Medicine, Department of Medicine, Center for Excellence in Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Anthal I P M SmitsSoft Tissue Engineering & Mechanobiology Division, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
Eindhoven University of Technology · NLBrigham and Women's Hospital · US

Funding

Improving Mitral Compensation In Ischemic RegurgitationR01HL141917 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI AIKAWA, ELENA, BISCHOFF, JOYCE E. · 2018 to 2021
$5.6M
Aortic valve microcalcificationR01HL114805 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI AIKAWA, ELENA · 2012 to 2016
$2.1M
NHLBI NIH HHS R01 HL114805NHLBI NIH HHS R01 HL141917
6 · The paper itself

Abstract

The creation of living heart valve replacements via tissue engineering is actively being pursued by many research groups. Numerous strategies have been described, aimed either at culturing autologous living valves in a bioreactor (

Indexed as

cardiovascular tissue engineeringelastogenesisextracellular matriximmunohistochemistryinflammationmacrophagesovine antibodiesvalvular interstitial cells

Identifiers

PMID30159315
PMCPMC6104173
OpenAlexW2885202758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.