Evidence map›Paper›PMID 30159254›Full record

ArticleFrontiers in oncology2018

Can Multi-Parametric MR Based Approach Improve the Predictive Value of Pathological and Clinical Therapeutic Response in Breast Cancer Patients?

Uma Sharma, Khushbu Agarwal, Rani G Sah, Rajinder Parshad, Vurthaluru Seenu, Sandeep Mathur, Siddhartha D Gupta, Naranamangalam R Jagannathan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Resistance to neoadjuvant chemotherapy in breast cancers: a metabolic perspective.Journal of experimental & clinical cancer research : CR · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. MR spectroscopy in breast cancer metabolomics.Analytical science advances · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Uma SharmaDepartment of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
Khushbu AgarwalDepartment of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
Rani G SahDepartment of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
Rajinder ParshadDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Vurthaluru SeenuDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Sandeep MathurDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Siddhartha D GuptaDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Naranamangalam R JagannathanDepartment of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential of total choline (tCho), apparent diffusion coefficient (ADC) and tumor volume, both individually and in combination of all these three parameters (multi-parametric approach), was evaluated in predicting both pathological and clinical responses in 42 patients with locally advanced breast cancer (LABC) enrolled for neoadjuvant chemotherapy (NACT). Patients were sequentially examined by conventional MRI; diffusion weighted imaging and

Indexed as

apparent diffusion coefficientbreast cancerclinical responsemagnetic resonance spectroscopyneoadjuvant chemotherapypathological responsetotal cholinetumor volume

Identifiers

PMID30159254
PMCPMC6104482
OpenAlexW2885695347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.