ArticleTranslational vision science & technology2018
Comparison of Visual Field Point-Wise Event-Based and Global Trend-Based Analysis for Detecting Glaucomatous Progression.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Artificial Intelligence-Guided Endpoint Selection for Neuroprotection Trials in Glaucoma.American journal of ophthalmology · 2026Article
- Labeling matters: A multicenter machine learning study on visual field progression in Glaucoma.PloS one · 2026Article
- Using the Rate of Global and Pointwise Microperimetry Change to Predict Structural Conversion in Intermediate Age-Related Macular Degeneration.Ophthalmology science · 2026Article
- Initial circumpapillary retinal nerve fibre layer rates of change predict glaucomatous progression.Eye (London, England) · 2025Article
- Risk Factors for Visual Field Progression in Primary Angle Closure Disease Over 10 Years: The CUPAL Study.Investigative ophthalmology & visual science · 2025Article
- Artificial Intelligence for Optical Coherence Tomography in Glaucoma.Translational vision science & technology · 2025Review
- Detection of glaucoma progression on longitudinal series of en-face macular optical coherence tomography angiography images with a deep learning model.The British journal of ophthalmology · 2024Observational
- Estimating the Distribution of True Rates of Visual Field Progression in Glaucoma.Translational vision science & technology · 2024Article
- Utility of targeted mean total deviation trend analysis for detecting progressive visual field changes in early-to-moderate stage glaucoma.Eye (London, England) · 2024Article
- A Bayesian Hierarchical Spatial Longitudinal Model Improves Estimation of Local Macular Rates of Change in Glaucomatous Eyes.Translational vision science & technology · 2024Article
- Association of macular vessel density and ganglion cell complex thickness with central visual field progression in glaucoma.The British journal of ophthalmology · 2023Article
- Foveal avascular zone vessel density is associated with visual field progression in early-stage glaucoma eyes with central visual field damage.Scientific reports · 2023Article
- Validating Trend-Based End Points for Neuroprotection Trials in Glaucoma.Translational vision science & technology · 2023Article
- Optical Coherence Tomography and Optical Coherence Tomography Angiography: Essential Tools for Detecting Glaucoma and Disease Progression.Frontiers in ophthalmology · 2023Article
- Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals.The British journal of ophthalmology · 2022Observational
- Pointwise and Region-Wise Course of Visual Field Loss in Patients With Glaucoma.Translational vision science & technology · 2022Article
- Glaucomatous Visual Field Progression in the African Descent and Glaucoma Evaluation Study (ADAGES): Eleven Years of Follow-up.American journal of ophthalmology · 2022Observational
- Predictors for elevation of Intraocular Pressure (IOP) on glaucoma patients; a retrospective cohort study design.BMC ophthalmology · 2022Article
- Improving event-based progression analysis in glaucomatous visual fields.Scientific reports · 2021Article
- Fundus-controlled perimetry (microperimetry): Application as outcome measure in clinical trials.Progress in retinal and eye research · 2021Review
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
purposeTo compare global trend-based and point-wise event-based analysis for detecting visual field progression in eyes with glaucoma.
methodsThe study included a cohort of 367 glaucoma eyes from 265 participants seen over a mean follow-up period of 10 years to develop a computer simulation model of "real-world" visual field results. Progression was evaluated with point-wise event-based analysis using the Guided Progression Analysis (GPA) and global trend-based analysis using the mean deviation (MD) and visual field index (VFI) measures. The specificities of the methods were matched based on a simulated dataset of stable glaucoma eyes, to allow an adequate comparison of their sensitivities for detecting progression.
resultsThe 5-year cumulative false-positive rate for the GPA alert of "possible progression" and "likely progression" (significant change from baseline at two and three consecutive visits, respectively) were 34.0% and 7.0%, respectively. At matched specificities, 27.7% eyes were detected as having progressed after 5 years using the GPA "likely progression" criterion, while 24.6% and 23.8% were detected as having progressed using the global trend-based analysis with MD and VFI, respectively. There was a moderate level of agreement between the GPA and global trend-based analyses.
conclusionsPointwise event-based and global trend-based methods had similar performances to detect glaucoma progression when rigorously matched for specificity. TRANSLATIONAL RELEVANCE: Although both point-wise event- and global trend-based analyses perform similarly, they could provide complementary information that could be exploited to improve the overall detection of progression in clinical practice and clinical trials.
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