Evidence map›Paper›PMID 30159143›Full record

ArticleBiomarker research2018

Dysregulated transcriptional networks in

Huining Kang, Nitesh D Sharma, Christian K Nickl, Meenakshi Devidas, Mignon L Loh, Stephen P Hunger, Kimberly P Dunsmore, Stuart S Winter, Ksenia Matlawska-Wasowska

Abstract read
In one paragraph

Article in Biomarker research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Haematologica · 2026
    Article
  2. Article
  3. Novel Diagnostic and Therapeutic Options forFrontiers in pharmacology · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huining Kang1Department of Internal Medicine, University of New Mexico, Albuquerque, NM USA.
Nitesh D Sharma2Department of Pediatrics, University of New Mexico, MSC105590, Albuquerque, NM 87131 USA.
Christian K Nickl2Department of Pediatrics, University of New Mexico, MSC105590, Albuquerque, NM 87131 USA.
Meenakshi Devidas3Department of Biostatistics, University of Florida, Gainesville, FL USA.
Mignon L Loh4Department of Pediatrics, University of California at San Francisco, San Francisco, CA USA.
Stephen P Hunger5Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA USA.
Kimberly P Dunsmore6Pediatric Hematology/Oncology, University of Virginia, Charlottesville, VA USA.
Stuart S WinterChildren's Minnesota Research Institute, Children's Minnesota, Minneapolis, MN USA.
Ksenia Matlawska-Wasowska2Department of Pediatrics, University of New Mexico, MSC105590, Albuquerque, NM 87131 USA.ORCID 0000-0002-9903-5793

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Children's Oncology Group Statistics &Data Center GrantU10CA098413 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ANDERSON, JAMES R · 2003 to 2013
$67.5M
WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
Support for Human Specimen Banking in NCI-Supported Cancer Clinical TrialsU24CA114766 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI RAMIREZ MILAN, NILSA DEL CARMEN · 2005 to 2014
$14.5M
University of New Mexico Clinical and Translational Science CenterUL1TR000041 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LARSON, RICHARD S · 2012 to 2014
$9.8M
NCATS NIH HHS UL1 TR000041NCI NIH HHS P30 CA118100NCI NIH HHS U10 CA098413NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NCI NIH HHS U24 CA114766
6 · The paper itself

Abstract

For children and young adults with T-lineage acute lymphoblastic leukemia (T-ALL), event free survival following relapse is < 10%. We recently showed that rearrangements of the mixed lineage leukemia gene (

Indexed as

Gene expressionKMT2ALeukemiaMicroarrayMLLT10T-ALL

Identifiers

PMID30159143
PMCPMC6107954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.