ReviewOpen access Macedonian journal of medical sciences2018
The burden of Diabetes, Its Oral Complications and Their Prevention and Management.
Review in Open access Macedonian journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06924372 (Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes), which is not on this map. Cited by 74 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes
Who cites it
74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 169 citations in OpenAlex.
- Early childhood caries and type 1 diabetes mellitus - Evidence on primary teeth and oral health: A systematic review.Biomolecules & biomedicine · 2026Pooled it
- Bidirectional association between periodontal disease and diabetes mellitus: a systematic review and meta-analysis of cohort studies.Scientific reports · 2021Pooled it
- Community interventions improve diabetes management and oral health in type 2 diabetes patients with chronic periodontitis.Scientific reports · 2025Trial
- A randomized controlled trial of an educational intervention to promote oral and dental health of patients with type 2 diabetes mellitus.BMC public health · 2020Trial
- Hyaluronic acid treatment outcome on the post-extraction wound healing in patients with poorly controlled type 2 diabetes: A randomized controlled split-mouth study.Medicina oral, patologia oral y cirugia bucal · 2020Trial
- Immediate implant-prosthetic dental rehabilitation of patients with diabetes using four immediately loaded dental implants: a pilot study.The Journal of international medical research · 2020Trial
- Dose-Dependent Protective Effects of Agmatine on Sublingual Gland Dysfunction and Pancreatic Damage in Experimental Diabetes: Evidence From Histological, Biochemical, and Immunohistochemical Analyses.Microscopy research and technique · 2026Article
- Enhancing Healing in Oral Surgical Procedures: A Review on Biomaterials, Growth Factors, and Tissue Engineering.Cureus · 2026Review
- Evaluating the cardio-protective effects ofCardiovascular endocrinology & metabolism · 2026Article
- Combining Hyaluronic Acid and Amino Acids for Improved Healing of Post-Extraction Tooth Socket in Type 2 Diabetes Mellitus Subjects: A Randomized Clinical Trial.Dentistry journal · 2026Article
- Clinical and Microbiological Profile of Oral Candidiasis: A Retrospective Study.Pathogens (Basel, Switzerland) · 2026Article
- Predictors of Self-Rated Oral Health Among Community-Dwelling Adults With Diabetes: A Cross-Sectional Analysis.Cureus · 2025Article
- Article
- Prevalence of Dental Caries and Its Associated Factors Among Diabetic Patients at Mbarara Regional Referral Hospital.Cureus · 2025Article
- Galactose Inhibits the Translation of Erg1 that Enhances the Antifungal Activities of Azoles AgainstAntibiotics (Basel, Switzerland) · 2025Article
- BuZhong YiQi Formula Alleviates Taste Disorders in Rats with Type 2 Diabetes Mellitus by Increasing the Number of Taste Buds and the Expression of Signaling Molecules in Taste Transduction Pathways.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Influence of Diabetes on Periapical Pathology in Treated and Untreated Teeth: A Cross-Sectional Comparison with Non-Diabetic Patients.Journal of clinical medicine · 2025Article
- A machine learning-based risk prediction model for diabetic oral ulceration.BMC oral health · 2025Article
- Oral Yeasts Carriage in Prediabetic Smokers and Nonsmokers.International dental journal · 2025Article
- Diabetic peripheral neuropathy detection of type 2 diabetes using machine learning from TCM features: a cross-sectional study.BMC medical informatics and decision making · 2025Observational
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus (DM), chronic disease, is a public health problem that affects 8.5% adult population worldwide. The number of adults with DM has risen sharply from 108 million in 1980 to 422 million in 2014. In 2012, 1.5 million individuals died because of DM and an additional 2.2 million deaths occurred because of high blood glucose level resulting in cardiovascular and other systemic diseases. DM brings huge economic loss to patients, their families, and healthcare systems. Globally, the cost of DM was US$1•31 trillion in 2015.
aimThis review article utilised the prevalence data of diabetes mellitus from the World Health Organization and International Diabetes Federation to provide a comprehensive picture of the disease in different parts of the world.
methodsElectronic databases such as Google Scholar, Medline via PubMed, Scopus, and Web of Science were used to search the literature. The library resources of Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia were used to retrieve studies on the topics of the present review.
resultsSystemic complications of DM include heart attack, kidney disease, limb loss, blindness, and peripheral nerve damage. More than 90% of diabetic patients were found to have oral manifestations. It is known that DM severely damages oral tissues causing periodontal disease, tooth loss, xerostomia, caries, burning mouth disorder, taste and salivary gland dysfunction, delayed wound healing, lichen planus, geographic tongue, and candidiasis. The evidence is mounting about a strong bidirectional relationship between DM and periodontal disease. Unfortunately, many diabetic patients are unaware of the association between DM and oral health, and only a small percentage of them visit the dentist for routine dental check-ups. Changes in lifestyles (control of blood glucose levels and self-care practices), regular dental check-ups with emphasis on periodontal assessment, and reinforcement of oral health instructions can effectively prevent oral complications of DM. Scaling and root planning are effective in improving glycemic control among diabetic patients.
conclusionDental professionals should be part of the multidisciplinary team that helps individuals with diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.