Evidence map›Paper›PMID 30158955›Full record

ArticleFrontiers in genetics2018

Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma.

Lushun Yuan, Guofeng Qian, Liang Chen, Chin-Lee Wu, Han C Dan, Yu Xiao, Xinghuan Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  3. Statistical genomics in rare cancer.Seminars in cancer biology · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Lushun YuanDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Guofeng QianDepartment of Endocrinology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China.
Liang ChenDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Chin-Lee WuDepartment of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Han C DanGreenebaum Cancer Center, School of Medicine, University of Maryland, Baltimore, MD, United States.
Yu XiaoDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xinghuan WangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wuhan University · CNFirst Affiliated Hospital Zhejiang University · CNHarvard University · USUniversity of Maryland, Baltimore · USZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis. And currently, there are no specific diagnostic biomarkers for ACC. In our study, we aimed to screen biomarkers for disease diagnosis, progression and prognosis. We firstly used the microarray data from public database Gene Expression Omnibus database to construct a weighted gene co-expression network, and then to identify gene modules associated with clinical features of ACC. Though this algorithm, a significant module with

Indexed as

adrenocortical carcinoma (ACC)biomarkercell cycleprogression and prognosisweighted gene co-expression network analysis (WGCNA)

Identifiers

PMID30158955
PMCPMC6104177
OpenAlexW2885218690

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.